Hi all,
On my naturopathic doctor's advice I took a coritsol test. Here are the results:
9AM level: 2.7 ng/ml (range 2.0 - 11)
9PM level: 0.30 ng/ml (range 0.2 - 1.3)
.... so, this is very low, esp. for a young, seemingly-healthy person. My ND recommended a few homeopathic remedies. I seem to be getting better, but mornings are still *brutal* for me, and I think this test is quite telling.
If anyone has experience with cortisol levels, please share your input. Thanks,
It's more typical for those of us with ME/CFS to have HPA axis (hypothalamus/pituitary/adrenal) dysfunction rather than autoimmune Addison's disease which causes the adrenal failure most endocrinologists are (semi) familiar with. In other words, it seems to be a brain problem rather than a structural problem with the adrenals.
The morning cortisol level should be up at the top of the range. So in my opinion, that result definitely needs to be followed up on. Did you only test twice a day? Most saliva tests are 4x/day.
The evening level is fine in my opinion. It should be near the bottom of the range at night so you can sleep.
If it were me, I would do a saliva test 4x/day if you have not already so you can see the rhythm across the day. You may be low all day and not just in the AM.
I would also consider getting a low dose ACTH stimulation test. The low dose test is better at determining those with secondary AI but it will still miss about half of those with adrenal problems so it is not perfect. But it is worth doing in my opinion especially with a doctor that understands adrenal issues.
Unfortunately, most endos are all focused on diabetes these days and finding an adrenal expert is tough. And most endos don't think anything of saliva tests at all which is bizarre considering they are so accurate that NASA uses them. Anyway, you may have better luck with a DO or integrative doctor. You just have to find one that is willing to prescribe more than just supplements or adrenal cortex extract. Obviously, I can't say for sure without knowing you or your history, but I would be surprised if you didn't need hydrocortisone replacement based on that AM cortisol value. So getting more testing is key...
HPA axis dysregulation can be caused by a myriad of issues - infection, methylation problems especially. Replacing the hormones can make you feel better while you work on the underlying issues.
Ema