Circadian rhythm, gut health, LPS, CD38, NAD+

[shoponl]

Came across this n=1 report, thought others might be interested too. The author has a subscription program for gut improvement, but I would think that a motivated/organized person could replicate the basics on their own if money was tight. No supplements needed... just circadian training, intermittent fasting, not eating at night, etc.

https://hackyourgut.com/2019/04/05/chronic-fatigue-syndrome-reversed-with-lifestyle-modification/

 

[kangaSue]

No supplements needed...

But adding in some Enterosgel to mop up LPS could have some significant added benefit.
https://www.nature.com/articles/s41598-019-42176-z
http://www.enteromedical.hu/applica...orbent-complex-treatment-bowel-dysbacteriosis

 

[valentinelynx]

One thing... it seems to me the author is confusing "exercise intolerance" with post-exertional malaise. I'm not sure how "exercise intolerance" is defined, but the author refers to "impaired muscle function" and says,"...as we get older, there is a gradual intolerance to exercise, particularly in the frail elderly." This kind of exercise intolerance occurs during exercise and limits the amount of exertion possible, which is different from PEM, which occurs hours to days after the exercise. In 2-day exercise studies, patients with ME/CFS can often show normal exercise capacity on the first day. The abnormalities don't show up until the second test.

This doesn't mean the protocol can't be helpful, just that the rationale is based on faulty information.

 

[keenly]

But adding in some Enterosgel to mop up LPS could have some significant added benefit.
https://www.nature.com/articles/s41598-019-42176-z
http://www.enteromedical.hu/application-enterosgel®-enterosorbent-complex-treatment-bowel-dysbacteriosis

But we need some E coli.

 

[keenly]

Came across this n=1 report, thought others might be interested too. The author has a subscription program for gut improvement, but I would think that a motivated/organized person could replicate the basics on their own if money was tight. No supplements needed... just circadian training, intermittent fasting, not eating at night, etc.

https://hackyourgut.com/2019/04/05/chronic-fatigue-syndrome-reversed-with-lifestyle-modification/

Sounds interesting.

 

[Hope4]

@keenly. Thanks, that link looks very interesting.

 

[kangaSue]

But we need some E coli.

Not the pathogenic strains though, or at least, they need to be kept in check. You can always take some Mutaflor (E coli Nissle) a couple of hours away from the Enterosgel.