Chris Kresser on Low Dose Naltrexone (LDN)

[PhoenixBurger]

This one just came out and Im still only mid-way through watching it, but as always, its super informative.

Thought some here might find it interesting.

https://www.youtube.com/watch?feature=player_detailpage&v=l8sWzoLtop4#t=107

-PB-

 

[Gondwanaland]

Here is a transcription
http://chriskresser.com/low-dose-naltrexone-ldn-as-a-treatment-for-autoimmune-disease

With interesting comments!

 

[CantThink]

When those microglia are chronically activated, as they are fibromyalgia and other pain disorders, it results in neurotoxicity and then this whole wide cascade of symptoms that are associated with all these conditions, and LDN essentially blocks that cascade by blocking the receptors on those microglial cells. This probably explains why in some of the studies so far LDN has been shown to reduce something called erythrocyte sedimentation rate, or ESR, which is an inflammatory marker that’s elevated in conditions like fibromyalgia.

From the link Gondwanaland posted.

My bolding - that's interesting as my ESR has been elevated for years, so maybe that's partly why LDN worked for me when I took it. I'm just about to start retaking it tonight, after a massive break. I'm really hoping it will get me out of bed/out the house.

I do suffer from a lot of pain and what I feel is inflammation. I found over time LDN transformed me by increasing my stamina, decreasing pain (somewhat) and improving my sleep (I felt I got deep sleep).

 

[Sporty]

I'm thinking of trying some. Good idea do you think?