Adult presentation of multisystem inflammatory syndrome (MIS) associated with recent COVID-19 infection: lessons learnt in timely diagnosis and manage

[SWAlexander]

This includes adults and children.

Abstract​

Multisystem inflammatory syndrome in adults (MIS-A) is an uncommon and under-recognised postinfectious manifestation that presents 4–6 weeks after COVID-19 infection. Patients affected tend to be young or middle-aged, from ethnic minority backgrounds and previously healthy. In addition to high fever and myalgia, there are a myriad of extrapulmonary symptoms and signs, including cardiac, gastrointestinal, neurological and dermatological involvement. Cardiovascular shock and markedly raised inflammatory markers are prominent features, while significant hypoxia is uncommon. Patients respond well to corticosteroid therapy, but failure of clinicians to recognise this recently identified phenomenon, which can mimic common conditions including sepsis, could delay diagnosis and treatment. Here we present a case of MIS-A in an adult woman, compare her presentation and management with other similar case reports, and reflect on how clinicians can learn from our experiences. https://casereports.bmj.com/content/14/10/e243114

MIS in adults? May 23, 2024
https://www.cdc.gov/mis/signs-symptoms/index.html
and: https://www.yalemedicine.org/conditions/multisystem-inflammatory-syndrome-in-children-mis-c

 

[linusbert]

where those vax'ed at least once or multiple times? i would be interested if they compared unvaxed vs vaxed people.

i know a personal case where one patient got long-covid after being infected with covid, but he was vaxed 1 or 2 weeks prior. so got immediate infection after the shot.
so i got suspicious that the vax could invite a covid infection with long covid potential through unknown mechanisms. i could imagine lowered immune response or capabilities in the time directly after the vax.