Have to pick you up on this point Cort, post #4 in this thread...someone else commented already on the other thread about this but it's a very important area and extreme caution is required to avoid repeating disinformation...
But viruses in the intestines of autistic children are not causing autism
A decade ago, for example, a British physician, Dr. Andrew Wakefield, claimed that vaccines against measles, mumps and rubella were linked to autism. One possibility he raised was that the live measles in the vaccines created inflammation in the intestines, allowing toxins or even viruses to move to the brain. One piece of evidence Dr. Wakefield and his colleagues offered was the finding that autistic children with intestinal disorders had high levels of measles viruses in their intestines.
Dr. Lipkin decided to test the claim in a different way, by looking for the viruses themselves. Teaming up with some of Dr. Wakefield’s original collaborators, he found no difference in the levels of measles viruses in the intestines of autistic and normal children with gastrointestinal disorders.
Just about every sentence of the above is confusing to me...
"A decade ago, for example, a British physician, Dr. Andrew Wakefield, claimed that vaccines against measles, mumps and rubella were linked to autism."
I'm pretty sure that isn't true. Dr Wakefield reported his scientific findings, which the other researchers involved have not rescinded: the findings remain valid. The story was picked up by the press and caused a widespread panic that MMR and autism may be linked, but I'm not sure that Dr Wakefield ever even explicitly claimed that MMR "may be" linked to autism, and I certainly don't think he went as far as to say that it IS linked to autism. The closest he got to saying that, as I understand it, was when asked by a journalist if he would vaccinate his own child with MMR, he reluctantly said 'probably not'. Dr Wakefield simply reported his scientific findings, which suggested such a link, this was picked up by the press, and Dr Wakefield was blamed for "scaremongering". Others know the history of all this far better than I, so I may be inaccurate in detail here, but my impression is that the idea that Dr Wakefield actually made this claim directly is a myth.
"One possibility he raised was that the live measles in the vaccines created inflammation in the intestines, allowing toxins or even viruses to move to the brain. One piece of evidence Dr. Wakefield and his colleagues offered was the finding that autistic children with intestinal disorders had high levels of measles viruses in their intestines."
This is rather confusing, in that as far as I'm aware this was the whole point of Dr Wakefield's paper, and I'm not aware of any other pieces of evidence he presented. This was pretty much the whole thing, as I recall it.
"Dr. Lipkin decided to test the claim in a different way, by looking for the viruses themselves."
Even more confusing. I'm not at all sure how this is a "different way" to what Dr Wakefield himself did. How did he find evidence of the viruses without looking for them?
"...he found no difference in the levels of measles viruses in the intestines of autistic and normal children with gastrointestinal disorders."
So, getting now to the heart of the matter: so what?!
This in no way proves the conclusion you drew from this Cort, that "viruses in the intestines of autistic children are not causing autism". It doesn't even prove that
measles viruses in the intestines of autistic children are not causing autism. Hell, it doesn't even
suggest that
measles viruses in the intestines of autistic children are not causing autism!
It might have been interesting if he had compared also the levels of measles viruses in the intestines of normal children
without gastrointestinal disorders. That might have allowed me to make some guesses about what the research might mean. But a comparison with children with gastrointestinal disorders (themselves ideopathic, remember), and the finding that they had measles viruses in their intestines as well, neither proves nor disproves anything. To me, if we could assume that these levels were lower in healthy children, Lipkin's findings would suggest a link between measles virus and both gastrointestinal disorders and autism. But in the absence of that data, and without more detail about how the 'autistic' children were selected and what the 'gastrointestinal disorders' were, Lipkin's findings seem to me to yield no information whatsoever about anything. The findings appear to be quite irrelevant to the important questions.
In fact, what a terrible experimental design, and how worryingly consistent that is with the other MMR/autism "debunking" studies I've seen. I've checked out the abstracts of 3 of those other studies, cited on wikipedia as the main evidence against an MMR/autism link, and provided you think carefully enough, it's not hard to see that the findings of all those other studies - despite the claims made about them - do not in any way rule out the possibility of a vaccine-mediated viral/retroviral link to autism.
In fact, consider the equivalent scenario for us: if a study compared XMRV levels in ME/CFS patients, autistic patients and patients with OI, and found similar levels in all of them, would that prove that XMRV is irrelevant to all 3 conditions? Do we have a similar but subtler non-sequitor to look forward to in the BWG experimental design? Seems we won't know until the results are in...
So: regarding the not-unrelated questions of trust, paranoia, fear, negativity etc...
I'm with the people who have no trust left in the medical research world in general, and especially not in the state sector of that world, and I'm with the people who are getting worried about how this is all unfolding right now.
The news that Lipkin was involved in a study that's being used as evidence against an MMR/autism link even though it is no such thing, is just about the last thing to inspire me with confidence. Put that together with the failure to live up to the promises of transparency over BWG Phase II, and the fact that once again crucial information is being withheld and this whole investigation is taking place behind closed doors, and I can only draw one firm conclusion at the moment: If the aim of Lipkin and of the BWG is to resolve the controversies over XMRV, then they can now
only do so by confirming the WPI findings. If these groups conclude that there is no link between XMRV and ME/CFS, then I will not believe them, because those groups have lost my trust in the past few weeks.
Dr Singh's patent application inspires huge confidence and I do remain fairly optimistic that the "right" kind of answers may arrive soon. But the withholding of information by the BWG and the veil of secrecy that continues to surround all this research has done a lot to undermine that confidence lately.
Can there be any clearer demonstration that the cause of paranoia, distrust and conspiracy theory is purely and simply the abundance of governmental secrecy and dishonesty and the withholding of information? Once you know that the bodies responsible for directing you towards the truth are lying to you, can you be blamed for trying to figure out the truth for yourself, based on the information you
can access, and the guesses you are obliged to make about the information that is withheld?
At the moment, there is very little I can know for certain, but among the things I do know for sure is that information is being actively withheld from the public in this matter, as it has been throughout. And if people are not being open and honest with me, even after promising they would be, why on earth would I trust those same people about anything, ever?