plz read this post :)

  1. S

    Does the Low Dose Naltrexone mechanism extend to other drugs?

    LDN works by transient antagonism of the opioid receptors, thereby tricking the body to upregulate them. Recently, I started taking a low dose of Clonidine for sleep. Clonidine binds to presynaptic alpha2 receptors, reducing adrenaline release. However, during the day I started having random...