• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

pathogenesis

  1. nerd

    Early Growth Response Gene Upregulation in Epstein–Barr Virus (EBV)-Associated Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

    This isn't the newest study of all but it hasn't been discussed yet and I think it deserves a separate post. It's a review of the existing evidence on latent EBV pathology in CFS/ME. Author: Jonathan Kerr Published: 26 October 2020 doi: 10.3390/biom10111484 Abstract
  2. nerd

    Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome

    Komaroff AL, Lipkin WI. Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of post-acute COVID-19 syndrome. Trends Mol Med. 2021 Sep;27(9):895-906 doi: 10.1016/j.molmed.2021.06.002 Epub 2021 Jun 7 PMID: 34175230 PMCID: PMC8180841 Abstract
  3. nerd

    Does viral selection pressure on the GABAergic system mediate the etiopathogenesis of ME?

    Please beware, this theory is highly speculative. However, considering the good risk-benefit ratio from associated solutions, I'd like to discuss it. One of the many unresolved questions of ME is the role of viral pathology and how it might mediate the ME etiopathogenesis. One of my existing...