• Welcome to Phoenix Rising!

    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of and finding treatments for complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia (FM), long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

    To become a member, simply click the Register button at the top right.

nmda

  1. frozenborderline

    My grand theory of etiology part II

    I've posted my unifying theory of etiology before. But part II is not quite done yet, however it has a lot of the parts there, just not all there, and not assembled properly or in order, so I've decided to kick off working on assembling it by posting about it here. None of the parts by...
  2. V

    What are symptoms of autoimmune encephalitis?

    I have a vague knowledge of it and have seen various posts scattered, so was wondering if those who have been through it can say some more about how it presented in them. Also interested in whether there is any connection to that and, for lake of a better term, (new onset) "neuropsychiatric" (I...
  3. frozenborderline

    Treatments that help attenuate opioid tolerance

    Opioids/opiates, specifically mu opioid agonists (occasionally delta) can be an important part of pain treatment and also help other me/cfs symptoms, such as insomnia or PEM. But they cause rapid tachyphylaxis (development of tolerance). This thread will be a long one in which we discuss all...
  4. P

    Did I find the cause of my ME/CFS + POTS? Combined 3ß-HSD and 21-hydroxylase-deficiency

    Recently, I wrote about the role of EZH2 in ME/CFS and POTS. A study by Monash University states that there is an upregulation of EZH2 in POTS syndrome.https://forums.phoenixrising.me/threads/role-of-ezh2-in-me-cfs-and-pots.80229/#post- 2276535 Now to what is new: The study says that not only...