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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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microglia

  1. SWAlexander

    ‘A silent killer’ - COVID-19 shown to trigger inflammation in the brain

    1 November 2022 Research led by The University of Queensland has found COVID-19 activates the same inflammatory response in the brain as Parkinson’s disease. The discovery identified a potential future risk for neurodegenerative conditions in people who’ve had COVID-19, but also a possible...
  2. SNT Gatchaman

    Mapping microglia and astrocyte activation in vivo using diffusion MRI (Garcia-Hernandez et al, 2022)

    Mapping microglia and astrocyte activation in vivo using diffusion MRI Raquel Garcia-Hernandez, Antonio Cerdán Cerdá, Alejandro Trouve Carpena, Mark Drakesmith, Kristin Koller, Derek K Jones, Santiago Canals, Silvia De Santis While glia are increasingly implicated in the pathophysiology of...
  3. SWAlexander

    The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Failure

    HYPOTHESIS AND THEORY article Although myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) has a specific and distinctive profile of clinical features, the disease remains an enigma because causal explanation of the pathobiological matrix is lacking. Several potential disease...
  4. nerd

    Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases

    Authors: Xiang X, Wind K, Wiedemann T, Blume T, Shi Y, Briel N, Beyer L, Biechele G, Eckenweber F, Zatcepin A, Lammich S, Ribicic S, Tahirovic S, Willem M, Deussing M, Palleis C, Rauchmann BS, Gildehaus FJ, Lindner S, Spitz C, Franzmeier N, Baumann K, Rominger A, Bartenstein P, Ziegler S...
  5. leokitten

    Recent Developments in TSPO PET Imaging as A Biomarker of Neuroinflammation in Neurodegenerative Disorders (2019) Werry et al

    An interesting read given the past TSPO-PET neuroinflammation studies on ME using first generation [11C]PK-11195 and now more recently second generation [11C]DPA-713, the pros/cons and limitations of these radioligands, and the development of novel third generation ligands. Recent Developments...
  6. leokitten

    An Inflammation-Centric View of Neurological Disease: Beyond the Neuron (2018) Skaper et al

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871676/ Inflammation is a complex biological response fundamental to how the body deals with injury and infection to eliminate the initial cause of cell injury and effect repair. Unlike a normally beneficial acute inflammatory response, chronic...