metabolomics

  1. GlassCannonLife

    Article: Evidence for Peroxisomal Dysfunction and Dysregulation of the CDP-Choline Pathway in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

    Just saw this article posted up on the ME/CFS News twitter. Link is here. Abstract: Emphasis above is my own. It made me think of a relatively recent (6-8 months ago..?) discussion I saw regarding plasmalogens. I made preliminary notes on them but didn't search further - perhaps this is...
  2. Pyrrhus

    A map of metabolic phenotypes in patients with ME/CFS (Hoel et al., 2021)

    A map of metabolic phenotypes in patients with ME/CFS (Hoel et al., 2021) https://insight.jci.org/articles/view/149217 A new metabolomics paper from the Norwegian team of Øystein Fluge and Olav Mella. In addition to providing additional support for the finding that ME cells have impaired...
  3. Pyrrhus

    Dysregulation of the Kennedy Pathway and Tricarboxylic Acid Cycle in ME/CFS (Che et al., 2021) (Pre-print)

    Dysregulation of the Kennedy Pathway and Tricarboxylic Acid Cycle in ME/CFS (Che et al., 2021) (Pre-print) Authors: Xiaoyu Che, Christopher R. Brydges, Yuanzhi Yu, Adam Price, Shreyas Joshi, Ayan Roy, Bohyun Lee, Dinesh K. Barupal, Aaron Cheng, Dana March Palmer, Susan Levine, Daniel L...
  4. nerd

    β-sitosterol reduces anxiety and synergizes with established anxiolytic drugs in mice

    Highlights In silico screen identifies β-sitosterol as a candidate anxiolytic drug β-sitosterol is anxiolytic in both naive and chronically stressed mice β-sitosterol alters the expression of immediate early genes Sub-efficacious doses of β-sitosterol and fluoxetine synergize when combined...
  5. BeADocToGoTo1

    Pancreas Damage, Exocrine Pancreatic Insufficiency (EPI) and Chronic Fatigue Syndrome (CFS)

    Since there are just a few very old posts linking pancreas issues with chronic fatigue syndrome, I write this in the hope that what I have learnt over the last 4 years might help others with similar life changing issues. It is an avenue worth looking into in your quest to feel better. It helped...