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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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  1. M

    Chronically high total IgM

    I have quite high IgM levels, that shocked my internal medicine doctor. He didn't believe it was correct, and ran the test again, and it was indeed correct. My total IgM continues to be high enough that an immunologist said I should be monitored for hematologic malignancies. She said high IgM is...
  2. JaimeS

    Poll on Immunoglobulin antibodies - Please respond if you've been tested!

    Just wondering how common it is for us to have documented immunodeficiencies here on PR. If you have had one of these (IgE for example) very HIGH, please select this response and elaborate in a comment. Thank you so much, guys! Please spread this around, inquiring minds want to know. :) Um...
  3. SOC

    Holy crap -- IgM deficiency

    I just got my immunoglobulin subset test results and I'm not happy. IgM: 19.8 (normal range 39.0 - 276.0) IgA: 125.0 (normal range 85.0 - 543.0) IgG: 738.0 (normal range 650.0 - 1650.0) Superficially, this looks like Selective IgM Deficiency (SIgMD) -- low IgM in the context of normal IgA...