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    Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.

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histone deacetylase

  1. nerd

    Does viral selection pressure on the GABAergic system mediate the etiopathogenesis of ME?

    Please beware, this theory is highly speculative. However, considering the good risk-benefit ratio from associated solutions, I'd like to discuss it. One of the many unresolved questions of ME is the role of viral pathology and how it might mediate the ME etiopathogenesis. One of my existing...
    • nerd
    • Thread
    • abortive infections etiology etiopathogenesis gaba histone deacetylase latent infections pathogenesis
    • Replies: 21
    • Forum: General ME/CFS Discussion
  2. nerd

    Histone Deacetylase (HDAC) Inhibitors and the Ketogenic Diet

    As someone who's advocated for the ketogenic diet in this forum, I think I should add the following warning about it. But please bear with me, there is more to it. The ketogenic diet (as a single therapy) can trigger viral reactivations. Here are three papers for reference. The first one...
  3. nerd

    Long-COVID and CFS/ME are not MCAS

    The inducement for this post is the growing publicity of the theory that Long-COVID is just a simple disease in disguise, such as MCAS, and that there is a quick solution around the corner. For MCAS, a low histamine diet would be a simple fix to all the problems. This is the subtext of the...
    • nerd
    • Thread
    • epigenetics histone histone deacetylase long covid long hauler mast cell activation mcas
    • Replies: 12
    • Forum: Mast Cell Activation (MCAS)