gut motility

My partner's MCAS has continued to worsen every day for months now. The symptoms are near constant, and worsen with anything they ingest. We've cut out nearly everything we could think of that could be worsening it, stopped all their vitamins, supplements, even moved house to escape from...

Has anyone got experience of Prucalopride or Fluconazole? Gastro has prescribed me a week of the antifungal Fluconazole for suspected Candida and a months trial of Prucalopride for poor oesophageal and gut peristalis (contractions that move food along). Apparently Prucalopride can in rare...

For context I shall put that i have no other options at this point than taking opioids for pain. I have exhausted most of the other issues. Also i dont think that my hemorrhoids and constipation are solely bc of opioids but i worded the title that way bc the opioids may have been last straw...