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amyloid

  1. SNT Gatchaman

    Quercetin binding accelerates prion fibrillation into proteinase sensitive and loosely structured amyloids (Yu et al, 2022)

    Quercetin binding accelerates prion fibrillation into proteinase sensitive and loosely structured amyloids Kun-Hua Yu, Cheng-Ping Jheng, Cheng-I Lee Amyloidoses are caused by the deposition of amyloid fibrils ascribed to protein misfolding. In this study, we examined the antiamyloidogenic and...
  2. SNT Gatchaman

    Amyloidogenesis of SARS-CoV-2 Spike Protein (2022, Nyström & Hammarström)

    Amyloidogenesis of SARS-CoV-2 Spike Protein Sofie Nyström, Per Hammarström Abstract SARS-CoV-2 infection is associated with a surprising number of morbidities. Uncanny similarities with amyloid-disease associated blood coagulation and fibrinolytic disturbances together with neurologic and...
  3. SWAlexander

    A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications

    Post-acute sequelae of COVID (PASC), usually referred to as ‘Long COVID’ (a phenotype of COVID-19), is a relatively frequent consequence of SARS-CoV-2 infection, in which symptoms such as breathlessness, fatigue, ‘brain fog’, tissue damage, inflammation, and coagulopathies (dysfunctions of the...