I've run my results through Genetic Genie, but I'm still not really sure where to start. Do I start with the red one (+/+) or are the yellow ones (+/-) just as important. Here are my results:- MAO A R297R rs6323 TT +/+ BHMT-08 rs651852 TT +/+ COMT V158M rs4680 AG +/- COMT H62H rs4633 CT +/- VDR Bsm rs1544410 CT +/- VDR Taq rs731236 AG +/- MTHFR C677T rs1801133 AG +/- MTR A2756G rs1805087 AG +/- MTRR A66G rs1801394 AG +/- MTRR A664A rs1802059 AG +/- And my detox ones CYP1B1 L432V rs1056836 GG +/+ SOD2 A16V rs4880 GG +/+ NAT2 R197Q rs1799930 AA +/+ CYP1B1 N453S rs1800440 CT +/- CYP1B1 R48G rs10012 CG +/- CYP2A6*2 1799T>A rs1801272 AT +/- CYP2D6 S486T rs1135840 CG +/- CYP2D6 100C>T rs1065852 AG +/- Any help in understanding where to start, and how to get my methylation & detox cycles working better would be appreciated. Blood test wise, I'm pretty good. Except B12 and Vit D. I've started a Vit B supplement which has all the active forms as well as 2000IU of Vit D per day.