If you take some blood tests to identify any ME/CFS-associated viruses in your body that are chronic active infections (as opposed to past dormant infections), then you can try some antivirals or immunomodulators to fight these active viruses, and some studies have shown this can bring some improvement in ME/CFS symptoms.
Details about the most important viruses to test for are given in the
roadmap of chronic fatigue syndrome (ME/CFS) blood tests and treatments (see the section: "
1st Round Tests: Common Microbial Infections in ME/CFS").
In the case of herpes family viruses like Epstein-Barr virus, HHV-6 and cytomegalovirus, Dr Lerner's study found that antiviral treatment needs to be taken for around 2 years before major improvement manifests. In the case of enteroviruses like coxsackievirus B and echovirus, oxymatrine treatment can bring improvements within two months.
Low-dose naltrexone (LDN) is not a test for viruses, but a treatment for ME/CFS. Note that
LDN may not work unless you also take vitamin D3.