I'm liking VanElzakkers vagus nerve infection theory. (Except for the repercussions of lack of effective treatment). It could encompass a number of infectious agents. HH-V, HS-V, enterovirus, borrelia. The Rituximab trials coming up, hoping to show autoimmune involvement, and the vagus nerve theory seem to be the strongest leads to primary causation that we have at the moment. (Someone with a better memory for upcoming research might like to correct me here). In any case, in August 2013 Michael VanElzakkers tweeted - 'Last Wednesday, met with a fantastic team including Anthony Komaroff; we're putting together a pilot study'. https://twitter.com/MBVanElzakker Does anyone know if this pilot study is going ahead ? If so, any dates or further information ?