Choline on the Brain? A Guide to Choline in Chronic Fatigue Syndrome
Discuss the article on the Forums.

Thoughts on my 23andme results?

Discussion in 'Genetic Testing and SNPs' started by skwag, Jan 22, 2015.

  1. skwag

    skwag Senior Member

    COMT V158M rs4680 AG +/-
    COMT H62H rs4633 CT +/-
    COMT P199P rs769224 GG -/-

    VDR Bsm rs1544410 CC -/-
    VDR Taq rs731236 AA +/+

    MAO-A R297R rs6323 TT +/+

    ACAT1-02 rs3741049 GG -/-

    MTHFR C677T rs1801133 GG -/-
    MTHFR 03 P39P rs2066470 GG -/-
    MTHFR A1298C rs1801131 GG +/+

    MTR A2756G rs1805087 AG +/-

    MTRR A66G rs1801394 AG +/-
    MTRR H595Y rs10380 __ no call
    MTRR K350A rs162036 AG +/-
    MTRR R415T rs2287780 __ no call
    MTRR A664A rs1802059 GG -/-

    BHMT-02 rs567754 CT +/-
    BHMT-04 rs617219 __ no call
    BHMT-08 rs651852 CT +/-

    AHCY-01 rs819147 TT -/-
    AHCY-02 rs819134 __ no call
    AHCY-19 rs819171 TT -/-

    CBS C699T rs234706 GG -/-
    CBS A360A rs1801181 AG +/-
    CBS N212N rs2298758 __ no call

    Here are the homozygous MTHFR mutations labeled as risk in @Valentijn 's thread

    rs1476413....G35A....TT +/+
    rs4846049....A372C...TT +/+

    I've done a bit of reading, but really haven't learned anything practical. Any input apreciated.
  2. Sherpa

    Sherpa Ex-workaholic adrenaline junkie

    My family all has the MAO-A R297R homozygous.

    This is not scientific, but I associate it with serotonin imbalance which can manifest as: anxiety, depression, OCD tendencies. We all respond well to taking P5P which seems to boost neurotransmitter levels and keep us more stable.

    Here is some information on MTHFR a1298c you might be interested in. Not as much is known about this mutation it seems.

    Good luck!
    skwag likes this.
  3. skwag

    skwag Senior Member

    Thanks Sherpa.

    Your association with MAO-A seems to hold, at least a little. It's definitely in the family. I feel like those tendencies can show up from time to time in me, but they're not dominant. On the other hand my memory is bad enough that I seem to forget how bad things were a few years ago. Interestingly, I've never found a benefit to P5P over B6, and I think it's likely that I was a little B6 toxic from supplementation a while back.

See more popular forum discussions.

Share This Page