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Tapanui Flu 10-year follow-up study pub 1997

Discussion in 'General ME/CFS News' started by CJB, Feb 10, 2010.

  1. CJB

    CJB Senior Member

    This subject came up in the Bell lecture thread and I did a quick search. Sounds like the same disease to me. This correlates with what Dr. Bell said about the percentage of his patients who recovered. He did also mention that further follow-up studies show the "recovered" patients taking a downturn.

    Titre du document / Document title

    Epidemic neuromyasthenia and chronic fatigue syndrome in West Otago, New Zealand. A 10-year follow-up

    Auteur(s) / Author(s)
    LEVINE P. H. (1) ; SNOW P. G. (2) ; RANUM B. A. (3) ; PAUL C. (4) ; HOLMES M. J. (5) ;

    Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

    (1) Department of Medicine, George Washington University Medical Center, Washington, DC, ETATS-UNIS
    (2) West Otago Medical Centre, University of Otago, Dunedin, NOUVELLE-ZELANDE
    (3) School of Pharmacy, University of Otago, Dunedin, NOUVELLE-ZELANDE
    (4) Department of Preventive and Social Medicine, University of Otago, Dunedin, NOUVELLE-ZELANDE
    (5) Department of Microbiology, University of Otago, Dunedin, NOUVELLE-ZELANDE

    Rsum / Abstract

    Background: In 1984, an outbreak of an illness characterized by prolonged unexplained fatigue was reported in West Otago, New Zealand. This outbreak resembled other reported outbreaks of epidemic neuromyasthenia in that affected individuals presented with a spectrum of complaints ranging from transient diarrhea and upper respiratory disorders to chronic fatigue syndrome (CFS). Objective: To obtain a perspective on the natural history of CFS not possible in clinic-based studies.

    Methods: Twenty-three of the 28 patients in the original report were contacted and asked to complete written questionnaires. Interviews were obtained in person or via telephone. Results: Ten (48%) of the 21 patients with satisfactory interviews appeared to meet the current Centers for Disease Control and Prevention (CDC) case definition of CFS, and 11 were classified as having prolonged or idiopathic fatigue.

    A return to premorbid activity was seen in most (n= 16) patients, although some reported the need to modify their lifestyle to prevent relapses.

    A female predominance was noted in those meeting the CDC case definition for CFS, whereas males predominated in patients diagnosed as having prolonged or idiopathic fatigue. Conclusions: The high proportion of patients recovering from CFS in the West Otago cluster suggests that epidemic-associated CFS has a better prognosis than sporadic cases. Female sex was confirmed as an important risk factor for CFS.

    Revue / Journal Title
    Archives of internal medicine ISSN 0003-9926 CODEN AIMDAP
    Source / Source
    1997, vol. 157, no7, pp. 750-754 (18 ref.)
    Langue / Language

    Editeur / Publisher
    American Medical Association, Chicago, IL, ETATS-UNIS (1960) (Revue)

    Mots-cls anglais / English Keywords
    Myasthenia gravis ; Neuropathy ; Mail inquiry ; Chronic fatigue syndrome ; Incidence ; Differential diagnostic ; Epidemiology ; Comparative study ; Prognosis ; Human ; New Zealand ; Oceania ; Nervous system diseases ; Neuromuscular diseases ;
    Mots-cls franais / French Keywords
    Myasthnie ; Neuropathie ; Enqute par correspondance ; Fatigue chronique syndrome ; Incidence ; Diagnostic diffrentiel ; Epidmiologie ; Etude comparative ; Pronostic ; Homme ; Nouvelle Zlande ; Ocanie ; Systme nerveux pathologie ; Neuromusculaire pathologie ;
    Mots-cls espagnols / Spanish Keywords
    Miastenia ; Neuropata ; Encuesta por correspondencia ; Fatiga crnica sndrome ; Incidencia ; Diagnstico diferencial ; Epidemiologa ; Estudio comparativo ; Pronstico ; Hombre ; Nueva Zelandia ; Oceania ; Sistema nervioso patologa ; Neuromuscular patologa ;
    Localisation / Location
    INIST-CNRS, Cote INIST : 2040, 35400006487640.0040
  2. ukxmrv

    ukxmrv Senior Member

    This review wasn't very popular with some of the patients in NZ. Some felt that he played down the level of disability that he reported. Also patients were left off and only found out about it afterwards. There was a lot of controversy.
  3. Gerwyn

    Gerwyn Guest

    what on earth are satisfactory interviews If they have to modify their life style to prevent relapses appeared to meet cdc criterea oh my god!
  4. ukxmrv

    ukxmrv Senior Member

    Yes, Gerwyn, those were exactly the sort of comments some of the patients made

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