I have had mild CFS for 20+ years (sore throat and fatigue, but manageable) until the last 3 where PEM and other things came up. Some other issues that I don't know if they are common with ME/CFS or not have popped up, so I thought I would see if there are others here that experience this? First one that has cropped up in the last 3 years, Fibrocystic breast disease. When I was young I did have one cyst that eventually went away, but this is different. It changes on almost a daily basis. One month it might be in the right breast, the next month it will be in the left. Then it will be in both. And then in 3 days it will be gone. Sometimes it feels like there are rocks in there! It definitely fluctuates with hormones, but is always different month to month. Next issue that has cropped up over the last year, is I get squeezed in the middle of the night from just below my boobs down into my thighs. I tell people I have a boa constrictor that sleeps in my bed. !!! It will squeeze me hard enough to wake me up, then subside after maybe 5 seconds, then 10 minutes or so later after I fall asleep, it does it again. When I tried to research this one, all I could find was the MS hug, which sounds like it is in the rib cage only, and lasts for a while before it subsides. So completely different? This seems to only happen in the summer when I have a difficult time keeping the bedroom cool. Last summer it nearly took my breath away, while this summer it has been mild. Third issue has been gone for a bit, but started about 18 months ago, and stopped about a year ago, it overlapped my boa constrictor. It felt like a buzzing ball of energy that actually travels around my body. I feel insane even talking about this one. It usually was about tennis ball sized, and traveled everywhere. The first time it happened it just sat near my heart and sent me to ER, but it has traveled around through my legs, my arms, my torso, and even my head. The time it was in my head I actually heard it as if someone took my electric toothbrush and put the handle to my skull. Also, by traveling, I don't mean today it is here, tomorrow it is there. I mean it literally moves around my body, like a child pushing a toy car around. But it does like to stop in one spot on occasion. It's favorite stopping part was my spine at my waist. It caused very severe back pain that I almost couldn't walk/sit with for a few months after the buzzing ball subsided. This also was a summertime issue, although I haven't had it this year. It has been gone long enough my back pain finally went away a couple of months ago. Both the boa constrictor and the buzzing ball only happened in the early morning hours of sleep. Not in the daytime. Anyone have any of these? Now you know why my doctor has thrown in the towel. I feel like someone has a voodoo doll of me.