I just got prescribed this by my doctor, not for ME, but for stress because of the way the DWP have been and continue to muck me about. I had been on Citalopram in the past for depression before i got ME, and found that left me feeling numb. I got over those issues and stopped taking it some time ago. So, we discussed going back on that, but i said i didnt want to feel numb and that i didnt feel i was depressed, and that my response was correct. She agreed, and suggested trying Sertraline as its good for stress too. She started me on 50mg, but I decided to start with half a tablet last night. By 4 o clock i was awake (unusual for me since being on Amitriptyline for sleep - which works great) and absolutely buzzing. I couldnt keep still, all my senses were overly sensitive, noise, touch, etc. My brain was spinning, it was like being struck by lightning. I've never taken recreational drugs, but this is the way I imagined them to feel. Horrible. I'm reluctant to continue unless the side effects are known to disappear after a few days/weeks. Anyone got any experience with it? The last thing i want to do is ruin my sleep again, as since starting Amitriptyline my sleep has never been better.