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Researchers discover potential genetic trigger of autoimmune disease

Discussion in 'Other Health News and Research' started by natasa778, Jun 29, 2016.

  1. natasa778

    natasa778 Senior Member

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    https://www.sciencedaily.com/releases/2016/06/160627125357.htm
     
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  2. Gemini

    Gemini Senior Member

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    Thanks for posting this interesting research @natasa.

    An excerpt from my input to the NIH RFI under gaps in ME/CFS research:
    • Interferon — More than two decades ago Wakefield and Lloyd noted the symptoms of ME/CFS bear a startling resemblance to those of interferon poisoning. In 2008 interferon genes topped the list in the Kerr, et al. gene expression study [PMID 18462164]. In 2013 new insights into the immunoregulatory properties of the interferon pathway during acute or chronic infections were published [Science, 12 April 2013 “An Interferon Paradox”]. Interferon signatures have been used to predict rituximab response in autoimmune disease [PMID 22540992.] And on June 3, 2016 at the IiME Conference in London Dr. Jo Cambridge, UCL, mentioned interferon may be involved in positive patient response to rituximab. It’s time to better understand the role of interferon and interferon signatures in ME/CFS, currently a gap in the research continuum.
     
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  3. Jesse2233

    Jesse2233 Senior Member

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    Why is this never mentioned?
     
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