International ME/CFS and FM Awareness Day Is On May 12, 2018
Thomas Hennessy, Jr., selected May 12th to be our international awareness day back in 1992. He knew that May 12th had also been the birthday of Florence Nightingale. She was the English army nurse who helped to found the Red Cross as well as the first school of nursing in the world.
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pentoxifylline

Discussion in 'General ME/CFS Discussion' started by Bdeep86, Jun 4, 2015.

  1. Bdeep86

    Bdeep86 Senior Member

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    I have been reading about this medication for its microglial and anti inflammatory properties. I did a search on here and it didn't yield much as far as anecdotal reports. Has anyone trailed this?
     
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  2. Hip

    Hip Senior Member

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    You might want to do a search on the related drug propentofylline, as you will find more info on this.
     
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  3. CFS_for_19_years

    CFS_for_19_years Hoarder of biscuits

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    There are a few posts here under the trade name Trental.
     
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  4. adreno

    adreno PR activist

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    It gave me a massive headache. And hives.
     
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  5. Ema

    Ema Senior Member

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    I actually just got a script for this to reduce inflammation.

    I hope it doesn't give me hives!!
     
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  6. Eeyore

    Eeyore Senior Member

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    I tried it for a time. It initially gave me a headache, but that went away with time. I lost a lot of weight on it - had no appetite at all. Overall, I'm not sure that it helped, although it did seem to help a bit with inflammation (redness in face lessened, less dry eye, etc.)

    It does increase bleeding tendency, and many ME patients have elevated tPA to start, and sometimes abnormal clotting and/or fibrinolysis, and antiphospholipid syndrome is not uncommon (although I don't have it). If you have any tendency to bleed you need to be careful - and INR would be sensible to check in advance as well as some basic measures of fibrinolysis - including d-dimer/FDP and t-PA.

    In general, I think it's a pretty safe med and a decent inflammatory. I'm not sure it really helps a lot in ME though - I've yet to hear of it really having a great effect in anyone.

    I wonder if the headache is a general effect or something particularly common in ME.
     

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