(wow a lot of researchers worked on this study) http://www.nature.com/ni/journal/v17/n10/full/ni.3543.html CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles Yew Ann Leong, Yaping Chen, Hong Sheng Ong, Di Wu, Kevin Man, Claire Deleage, Martina Minnich, Benjamin J Meckiff, Yunbo Wei, Zhaohua Hou, Dimitra Zotos, Kevin A Fenix, Anurag Atnerkar, Simon Preston, Jeffrey G Chipman, Greg J Beilman, Cody C Allison, Lei Sun, Peng Wang, Jiawei Xu, Jesse G Toe, Hao K Lu, Yong Tao, Umaimainthan Palendira, Alexander L Dent Nature Immunology 17, 1187–1196 (2016) doi:10.1038/ni.3543 Received 19 July 2016 Accepted 29 July 2016 Published online 03 August 2016 Abstract During unresolved infections, some viruses escape immunological control and establish a persistant reservoir in certain cell types, such as human immunodeficiency virus (HIV), which persists in follicular helper T cells (TFH cells), and Epstein-Barr virus (EBV), which persists in B cells. Here we identified a specialized group of cytotoxic T cells (TC cells) that expressed the chemokine receptor CXCR5, selectively entered B cell follicles and eradicated infected TFH cells and B cells. The differentiation of these cells, which we have called 'follicular cytotoxic T cells' ............................................ I myself when I had EBV (mono) severely as a teen (extremely sick for 10 weeks to point i had seizures and passouts due to the EBV) have always thought since then I have something wrong or different with my immune system to others. (I got ME 10 years after that mono), so maybe its due to something being wrong with this new type of cell which can kill mono infected cells?. I wish I could have my follicular cytotoxic T cells tested.