New Atmosphere, New Vision: Gibson and Whittemore Kick Off Invest in ME Conference 2016
Mark Berry reports on Dr. Gibson's introduction and Dr. Whittemore's keynote speech, at the 11th Invest in ME International ME Conference in London.
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New Stanford Study

Discussion in 'Latest ME/CFS Research' started by Jane Norris, Oct 18, 2013.

  1. Jane Norris

    Jane Norris

    Would you like to be in a study for people with Chronic Fatigue Syndrome?

    Stanford University is seeking participants for a Clinical Trial entitled: Phase 2, Randomized, Double-Blind, Placebo Controlled, Parallel Group Study to Evaluate the Safety, Tolerability, and Efficacy of Methylphenidate Hydrochloride as a treatment for Chronic Fatigue Syndrome in Patients taking a CFS-Specific Nutrient Formula.

    Our team is looking for participants between 18 and 59 years old who suffer from cognitive impairment who are not on CNS stimulants or valcyte. This study requires 4 visits at Stanford as well as 4 telephone contacts. As part of the study, participants will be compensated for their time at the Stanford location.

    Participation in the study involves doing a
    20-30 minute phone-screening interview.

    If you are eligible, you will be invited to come to Stanford for:
    3 study visits and 1 screen visit within a 3 and 1/2 month period.

    You will be compensated with $50 4-6 weeks after each study visit (3 visits) at Stanford to reimburse you for your time and participation.

    If you are interested in participating or have any questions, please contact one of the study coordinators,

    Jane Norris, at (650) 723-8126 or
    Ian Valencia, at (650) 723-7328,

    For general information about participant rights, contact
    readyforlife likes this.
  2. A.B.

    A.B. Senior Member

    You're probably going to make CFS patients worse in the long term by giving them stimulants.
    aimossy, vli and Valentijn like this.
  3. Valentijn

    Valentijn Senior Member

    Yeah, it's never sustainable. And drugs messing with dopamine scare me. And don't seem like they'd help much since I've never heard of dopamine production being particularly low in ME patients. In fact, I think my last values were quite high.

    The NRI aspect might help a bit, but maybe not since it's so weak compared to the dopamine effect. But I have found a pretty specific NRI (Strattera) to be quite helpful for Orthostatic Intolerance. And suppressing the ADRA2A gene expression more directly with Yohimbe has been even more effective for OI, PEM, and reduced GI motility in the past week or while I've been trying it.

    ME/CFS isn't "fatigue". We really don't need stimulants, and generally can't handle them anyhow.
    roxie60, rosie26 and aimossy like this.
  4. A.B.

    A.B. Senior Member

    Fatigue is difficult to define. It's not incorrect to say that ME/CFS patients suffer from fatigue in my opinion, it should just be clarified that this is not the usual fatigue that everybody knows.

    My experience with a dopamine agonist was: one month doing pretty well, followed by a horrific crash lasting six months. Ever since I'm scared stimulants.

    The underlying illness is more complex than a lack of motivation that could be fixed with drugs that increase drive and motivation.

    I believe the lack of motivation is a natural and correct response by the body attempting to conserve what little energy is left.
    Valentijn likes this.
  5. aimossy

    aimossy Senior Member

    sounds dangerous to be honest ,whats the rationale behind that as a study?
    Valentijn and vli like this.

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