Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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My low GABA levels - Interesting rabbit hole

Discussion in 'General ME/CFS Discussion' started by Beyond, Nov 12, 2013.

  1. Beyond

    Beyond Juice Me Up, Scotty!!!

    Murcia, Spain
    So I got tested once two years ago and I was awfully defficient in GABA. Probably the most severe defficiency I have ever showed in tests.

    I have already posted this, but, no harm in posting it here again for those that didn´t saw it!

    Is interesting to note it decreases digestive enzyme production (!). I also was very defficient in Taurine, the symbiotic aminoacid of GABA and needed for it to work properly.

    I have also high prolactin, which is lowered by GABA (low, checked) and DHEA (low, checked). And chronic pain related to tense muscles. Lastly I have low glutamic acid and B6 levels and plenty of GAD1 mutations.

    So I am very eager to eat these PharmaGABA pills...
    Last edited: Nov 12, 2013
    Learner1 likes this.
  2. NotThisGuy

    NotThisGuy Senior Member

    Have u tried to supplement glutamic acid with b6 in the meanwhile?
    I stopped tolerating B6 (dont know why).
    But maybe my low glutamic acid is why B6 stopped working.
  3. overtheedge

    overtheedge Senior Member

    I'm interested in seeing how this goes
  4. Gingergrrl

    Gingergrrl Senior Member

    @Beyond Have you ever been tested to see if you have the autoantibody against GAD65? I have this and it attacks the enzyme that allows glutamate to convert to GABA. Prior to getting IVIG, I was tortured by an insane startle reflex to every day noises and possibly had one "startle seizure" to the fire alarm although we are not certain. After IVIG, the startle reflex has disappeared and never returned. It might be worth getting tested for. GAD65 often links to diabetes but in my case, it did not.
    sb4 likes this.

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