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Is the return of Ulcerative Colitis part of healing under Freddd's protocol?

Discussion in 'Gastrointestinal and Urinary' started by Enigmatic, Aug 15, 2014.

  1. Enigmatic


    I have a history with Ulcerative Colitis. It first appeared in the late 90's and was then dormant until 2011/2012 when I had a couple of attacks. It then went into remission.

    I've since had a lot of other health problems that resulted in me coming across this site and starting the @Freddd protocol.

    When following it properly, I started seeing great improvements day on day and week on week. All sorts of healing going on and feeling better.

    Then about two weeks ago I started to have GI problems that lead to intestinal bleeding and basically I am no experiencing Ulcerative Colitis symptoms again.

    This is nowhere near as severe as what I've experienced but it is annoying to have it back. I've done so much diet and lifestyle wise that I have no trigger or reason for UC to return to my life.

    Is it possible that this is some form of healing or reaction to the healing elsewhere in my body and I'm just ridding myself of the remnants that were in my body?

    I will discuss with my GP next week but I'm not confident of getting proper medical advice. The specialist I saw previously was adamant diet/lifestyle had no bearing and the only solution was terrible drugs that he prescribed or surgery despite me showing I had gone into remission based purely on diet changes.
  2. Freddd

    Freddd Senior Member

    Salt Lake City

    Hi Enigmatic,

    I don't know how or if at all Ulcerative Colitis is connected to these nutrients or why it would flair now. Allow me to speculate upon whatever possibilities I can see. For starters we are dealing with an epithelial tissue here and epithelial tissues are strongly affected by the Deadlock Quartet. Also remember that when (relatively) low doses are used (I have no idea what doses you are using, just a general scene setting for speculation) that B12 and folate are applied in "triage" levels, so some tissues can be healing like gangbusters and other tissues are having severe insufficiency or deficiency reactions. "Partial" methylation block, appears "partial" by triage layers.

    AdoCbl (with zinc) has a huge influence on inflammation and deals with it rapidly, generally. When starting l-methylfolate a donut hole deficiency can occur on some triage levels (this is part of the "partial" of partial methylation block) as other levels heal. This lack of l-methylfolate can cause rapid onset of widespread inflammation, tissue malformation, hyper responses, demyelination lesions, possibly autoimmune responses, asthma, allergies, MCS, angular cheilitis, G.I. sores and lesions from mouth to anus (ulcerative colitis? who knows?).

    I had areas of possible RSD with skin changes. These areas changed over time. When a certain level started healing the area it turned kind of red and subsurface tissue grew rapidly and I sloughed off the whole area of changed skin with normal skin remaining. Others have also reported a local worsening of epithelial tissues early in healing followed by a normalizing of the area. Some may not have had normalization. I don't know. Many don't mention it.

    Also, whey, NAC, glutathione, HyCbl, folic acid, folinic acid and vegetable folates and any number of medications can cause or contribute to partial methylation block of various characteristics.

    I hope this gives you some ideas. I hope you find something that helps.
    Enigmatic likes this.
  3. Enigmatic


    @Freddd Thanks again for taking the time to provide a detailed response.

    My dosing is as follows:

    1x Solgar, Folate As Metafolin, 800 mcg

    Between meals/away from Folate
    0.5 tsp Now Foods, Potassium Gluconate
    15ml Jarrow Formulas, Liquid Carnitine, Lemon-Lime Flavour

    1x Solgar, Folate As Metafolin, 800 mcg

    Between meals/away from Folate
    0.5 tsp Now Foods, Potassium Gluconate

    1x Solgar, Folate As Metafolin, 800 mcg

    At other times of the day I will use about 2 Enzymatic Therapy, B12 Infusion as I find this gives me a different type of healing to the Jarrow B12 that I've used. I also use a crumb of Anabol Naturals, Dibencoplex 10,000 when I take the B12.

    I had to build up to the liquid Carnitine and could feel a reaction as I increased each dose. I'm now up to 15ml and have gone passed this amount and felt no reaction like I had before.

    Folate has also been built up slowly so could be the weak link here. I've been at 1/2 a Solgar tablet for a while but have increased this to 3/4 and now to 1 whole. I will take this at least 3 times per day.

    I take the Potassium Gluconate at random times through the day away from Folate and will actually have 3-4 glasses of water with it in during the day.

    I do take some other supplements but none of those listed. I do eat some veggies that will contain folates e.g. Broccolli. The other supplements I use include the following (mentioned in case there should be something here to be avoided):
    • Jarrow Formulas, Toco-Sorb, Mixed Tocotrienols and Vitamin E, Vitamin E (as d-alpha tocopherol) 15 mg
    • Jarrow Formulas, TMG, Trimethylglycine, 500 mg
    • Jarrow Formulas, PS 100, Phosphatidylserine, 100 mg
    • Now Foods, Super Enzymes
    • Creon 25000 Capsules
    • 2x Now Foods, L-Methionine, 500 mg (on waking)
    • 1x Now Foods, 5-HTP, 100 mg (before bed)
    For my Pyroluria:
    • Now Foods, P-5-P, 50 mg
    • Now Foods, B-6, 100 mg
    • Thorne Research, Double Strength Zinc Picolinate (each 30mg)
    • Thorne Research, Pic-Mins - Zinc (as Zinc Picolinate) 15 mg
    I'm going to ask my GP when I see him about needing to continue the use of the Creon 25000 Capsules. I'm on quite a high dose and now wondering whether these are now having an adverse impact. The reference material makes reference to fibrosing colonopathy being caused by the capsules.
    Last edited: Aug 17, 2014
  4. Enigmatic


    Well I've made a few changes since the last post.

    Don't normally like to do more than one at a time but I noticed an onset of symptoms after taking the Creons so I stopped those. I don't get the rush to the bathroom now that used to occur after taking them.

    I've also worked to increase my intake of Methyl Folate. I was at 800 mcg and have now worked up to 1.2 mg per dose. I'm taking these every four hours so getting 4 in each day.

    I am feeling some benefits from taking them but some of my UC symptoms are actually worse. I get more discomfort when I go and I have pains within my ascending colon. I'm also feeling more fatigued and tired but I'm putting this down to the UC and the loss of blood.

    Benefits appear to be an ease in symptoms from about 3/4PM onwards which would be after I've had my third dose of the day.

    My theory now is that I still need to increase my Methyl Folate further. I've been able to switch up doses at 200mcg extra reasonably well so will try and nudge up doses toward 2mg per dose.

    @Freddd does this sound reasonable to you? I'm taking Potassium through the day - do I need to increase the B12?

    Have seen my GP and he is concerned that I should have a return of UC. He had no issue with me increasing my Methyl Folate but wants me to have a colonoscopy and added some further blood tests to those I wanted to do.

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