I'm new here. I will upload my (and my husband's) GG methyl. profile obtained through 23andme testing. I have very low ferritin now (9 mg/dL). I have iron-deficiency anemia and have recently been low in hemoglobin, though not now. My iron is now 118, and my hemoglobin is now 13-14. I am having trouble with tolerating iron in any supplement or IV form. My doctor says I may have a rare parasite from when I was on a missions trip in Africa 30 years ago (I know, hard to believe), but if that turns out negative, she's at a loss what to do to raise my ferritin. My husband found some info through this website and www.stopthethyroidmadness.com/ferritin/ about other possible explanations such as high copper, high heavy metals (this is true of me), etc. Recently, we got our results back and it looks like I have the B12 double whammy, both a homozygous MTR and a homozygous & heterozygous MTRR. According to @caledonia's Guide (if I understood correctly), this means the double whammy. I'm wondering if anyone knows the role of the B12 cycle and iron/ferritin and if I could find scientific articles to help my doctor? My file is the first, my husband's is the second. We also have the detox panel but that was less bad for me. I can upload it if needed.