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Huge New Research into Neuro-Immune mechanisms: could impact it impact ME/CFS?

Mohawk1995

Senior Member
Messages
287
"Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury"

Came across this article which is by the same researchers that recently discovered the "Glymphatic" system (small lymphatic pathways formed by glial cells in the brain). Both of these discoveries are turning much of what we think about the immune system and the brain on its head including the "Blood Brain Barrier".

Since it appears that ME/CFS is highly Neuro-Immune, it stands to reason that these discoveries may help us gain a better understanding of the mechanism(s) behind ME as well as Altzheimers, MS, concussion, CTE and Acute Brain Injury.

The most interesting fact is that these Lymphocytes are heavily involved in the digestive tract and may now provide an explanation for the Brain-Gut connection. They also seem to sit or "Ride" right on top of the Glymphatic channels which is being researched even further as to why.

Fascinating after all the research we have done in this area that these two discoveries have just come out in the past 2 years.

Type 2 Innate Lymphocytes article:
http://jem.rupress.org/content/early/2016/12/16/jem.20161982

Article on Glymphatic System article:
http://journals.lww.com/neurotodayo...udy_Suggests_Brain_Is_Connected_to_the.1.aspx