aaron_c
Senior Member
- Messages
- 691
Hi Yall,
I just looked up Rs662 on 23andme (A PON1 snp) and found that I have the TT genotype according to them, but the AA genotype according to dbSNP. The snpedia page lists my options as either A or G. Other genes on 23andme do not have different genotypes for 23andme and dbSNP.
I understand that in DNA A will always be paired with T and G will always be paired with C, so it makes sense that they are saying the same thing in different languages, as it were, but I don't understand why they are sometimes different and sometimes the same. In particular, it makes it difficult to know what is happening when there are three possible nucleotides (I think I have seen this happen...but perhaps I did not understand what I saw.)
I would appreciate any explanation yall can offer.
Thanks a lot!
I just looked up Rs662 on 23andme (A PON1 snp) and found that I have the TT genotype according to them, but the AA genotype according to dbSNP. The snpedia page lists my options as either A or G. Other genes on 23andme do not have different genotypes for 23andme and dbSNP.
I understand that in DNA A will always be paired with T and G will always be paired with C, so it makes sense that they are saying the same thing in different languages, as it were, but I don't understand why they are sometimes different and sometimes the same. In particular, it makes it difficult to know what is happening when there are three possible nucleotides (I think I have seen this happen...but perhaps I did not understand what I saw.)
I would appreciate any explanation yall can offer.
Thanks a lot!