lansbergen
Senior Member
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You could run a few tests to see that, no?
If there were tests for every dangerous pathogen but sadly there ain't.
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You could run a few tests to see that, no?
People on the resistant starch thread are reporting that tiny doses or prebiotics and/or probiotics are causing them problems. This is such a contrast with what the Borody FMT study seems to show.
I wonder if the intolerance /bad reaction to probiotics could be linked to SIBO - presence of (otherwise good) bacterial where they shouldn't be present. In which case taking probiotics is adding insult to injury ...?
The supplement included a number of species, but I think my reaction may have been due to lactobacillus salivarius. It's a strange probiotic that acts a bit like an antibiotic, in that it kills quite a lot of other gut bacteria, which is why it's sometime used for diarrhoea. And since my nasty reation to that, I can't tolerate any off-the-shelf probiotics any more.
I have considered FMT in the past, however at this point I dare not, and not just because of the pathogen risk. I certainly don't want a huge load of lactate-producing species dumped in my GI tract.
I'm glad you mentioned that, Sasha. (It will make me extra-extra-cautious about trying any further probiotics.) Sounds like a horrible reaction.For example, when I took Prescript Assist last year, it gave me terrible migraines and an outbreak of cold sores. With C. Butyricum, I got joint pain. All sorts of stuff seems to be going on with people!
Not sure why pills would be safer? Both can be screened for known pathogens. However, the problem of species selection still stands. As said, I wouldn't want a load of lactate producing species dumped in my gut. That might be fine for someone otherwise healthy, but PWMEs often have problems clearing excess lacate. I am much more interested in select lactate utilizing species that produce butyrate.In which case a trial of a 'synthetic' poop pill might be worth considering? Saying that not sure if/when those will be available, and how heavily regulated, ie if rx will be needed. Then there is the SIBO issue to consider, if taking orally, and god knows what else... But at least the unknown pathogen risk should be next to zero?
I'm glad you mentioned that, Sasha. (It will make me extra-extra-cautious about trying any further probiotics.) Sounds like a horrible reaction.
Not sure why pills would be safer? Both can be screened for known pathogens.
For me personally, it's a helpful note of caution after my recent experience of probiotics.I don't think it's necessarily an argument for avoidance, just for starting at low doses.
The appeal of this hypothesis is that these disorders have arisen in parallel with big changes in population diets. Our gut bacterial population is strongly influenced by what we eat. I think its unlikely its completely correct, but if its only correct in half the cases then that is hundreds of millions of people who may be helped. I think this is an area that is getting more and more attention from scientists.It is my personal belief that bacterial dysbiosis plays a large part in the pathogenesis of all kinds of currently mysterious neurodegenerative and immune diseases
What can be done to minimize risk, butt this still requires a lot of research, is to isolate beneficial strains and culture them as a pure strain. Then strains can be mixed to develop the therapeutic treatment. This will not completely eliminate risks from bacterial viruses or other pathogens living in bacteria.If there were tests for every dangerous pathogen but sadly there ain't.
got an FMT and her depression went from 8 to 2 overnight...she is fully healed.
Well, that's pretty impressive! -- Interestingly, there are reports that people who begin using coffee enemas notice immediate improvements in depression. It was actually first documented in the New England Journal of Medicine back in 1922.