Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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EBV IGG treatment

Discussion in 'Antivirals, Antibiotics and Immune Modulators' started by hrosenkrantz, Sep 18, 2016.

  1. hrosenkrantz


    My husband, who may have CFS, recently had some bloodwork done. His EBV Ab VCA, IgG was 212.0 and EBV Nuclear Antigen Ab, IgG 512.0.

    Both are listed high on labcorp. IgM not tested.

    Have your doctors given antivirals with titers like this>
  2. Hip

    Hip Senior Member

    In Professor Jose Montoya's study on ME/CFS patients, when the testing is performed using the EBV test from Quest Diagnostics, he considers an EBV-EA of 1:160 or more and an EBV-VCA IgG 1:640 or more to be high.1

    Note that:
    EA = early antigen
    VCA = virus capsid antigen (also denoted by CA)
    EBNA = Epstein-Barr nuclear antigen

    I am not sure how to translate this to the Labcorp figures. EBV antivirals such as Valtrex or Famvir at a dose of 1,000 mg four times daily can improve ME/CFS symptoms, but it takes around 2 years before the benefits appear, according to Dr A Martin Lerner's research.

    In Dr Lerner's study on 142 ME/CFS patients with herpes virus infections, 75% of patients responded to the appropriate antiviral treatment (Valtrex/Famvir for EBV, and/or Valcyte for HHV-6 and cytomegalovirus); the average improvement in ME/CFS symptoms was a 2-point increase on the Energy Index Point Score scale (for example, as a result of antiviral treatment, an average patient may go from from level 4 to level 6 on this scale).1

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