Invest in ME Conference 12: First Class in Every Way
OverTheHills wraps up our series of articles on this year's 12th Invest in ME International Conference (IIMEC12) in London with some reflections on her experience as a patient attending the conference for the first time.
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Disrupted brain circuitry for pain-related reward/punishment in Fibromyalgia. 1/2014 Arthritis Rheum

Discussion in 'Other Health News and Research' started by *GG*, Feb 17, 2015.

  1. *GG*

    *GG* senior member

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    Concord, NH
    CONCLUSION:
    FM patients exhibit disrupted brain responses to reward/punishment. The ventral tegmental area is a source of reward-linked dopaminergic/γ-aminobutyric acid-releasing (GABAergic) neurotransmission in the brain, and our observations are compatible with reports of altered dopaminergic/GABAergic neurotransmission in FM. Reduced reward/punishment signaling in FM may be related to the augmented central processing of pain and reduced efficacy of opioid treatments in these patients.

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