I read one of the posters earlier saying to avoid taking the bicarbonate near meals, I agree with that. if anyone starts to experience chronic constipation or IBS like symptoms that could be because of low stomach acid, I don't know how likely it is that taking sodium bicarbonate would cause prolonged low stomach acid but those symptoms I mentioned are what I had to deal with for years before I tried supplementing Betaine HCL with meals to raise stomach acid and that terrible constipation and pain went away in days. Admittedly though I may be wrong as I also started taking digestive enzymes with meals the same day as the betaine HCL so it may have been an enzyme problem. Just a heads up
I’m so sorry to hear that. Thank you for the reply.
I take D-Ribose & L-carnitine. I’m not seeing any improvements really. How much should I start off with the sodium bicarbonate?
have you tried Coenzyme Q10? D-Ribose, carnitine, and coq10 have really helped me. Anytime I read something about the mitochondria these three seem to pop up, magnesium pops up a lot too and adenosylcobalamin though I haven't tried that last one. About the ribose, I've been getting great results taking a small dose of it every thirty minutes, never got very much out of it when I took 5g's three times a day. The half life of ribose is something along the lines of 30-40 minutes which, I think, may be why it is working so well for me in small doses throughout the day. The doctors who advocate this dosing schedual that I am aware of are Dr. Sinatra and Dr. Myhill, I didn't come up with it.
I usually put 2.5g's in half a glass of water and drink a third that glass every thirty minutes and then repeat all throughout the day. Found this post the other day which interested me, reading that people take up to 60 grams of ribose daily I may try increasing my dosage. here's the post
http://www.hhhummingbirds.com/coq10-carnitine-mg
Ubiquinol has been shown to peak blood levels 6 hours after ingestion.
Thousands of patients have taken D-ribose at dosages up to 60 grams per day with minimal side effects.
We do know that M.E. has some similarities to Parkinson’s and can be a similarly disabling neurological disease and that (anecdotally) those with moderate – severe M.E. will most often need doses the same as those listed for Parkinson’s disease, in order to experience an improvement in quality of life. (1200 mg of ubiquinone daily is often quoted as a standard dosage for Parkinson’s patients.) The dosage of CoQ10 in M.E. can be guided by blood levels of CoQ10 or by raising the dose until the patient experiences significant improvement, or both. The maintenance dose of CoQ10 should then be adjusted downwards as much as possible, without losing the benefits. For patients that are severely affected the maintenance dose may need to stay the same as the initial dose, in order to prevent relapse. CoQ10 should be taken in 2 – 3 divided doses (with food). Do not take medium - large doses all at once.
Nutritionist Robert Crayhon explains that mitochondrial supports ‘should be combined with antioxidants to compensate for the increased production of free radicals that is a by-product of greater energy output. Older people especially need to take extra antioxidants to compensate for this.’ Lipoic acid is one of the most important antioxidants, along with vitamin E and vitamin C. CoQ10 is also an antioxidant. Dr Sinatra recommends that 50 -100 mg of lipoic acid (and also a daily multivitamin, extra vitamin C and fish oil) always be taken along with the ‘awesome foursome.’ He states that to help neutralise free radicals, nurture your mitochondria and delay aging, life-long supplementation with CoQ10, L carnitine, lipoic acid and vitamins C and E is essential.
Dr. Myhills recommendation is 300mg CoQ10 for several months then reducing to 100mg per day
I'm planning on judging it based on blood testing
