Combination of pregabalin with duloxetine for fibromyalgia: A randomized controlled trial

[shannah]

Out of Canada:

Abstract

Fibromyalgia is a syndrome characterized by chronic widespread pain and associated with sleep disturbance, depression, fatigue and cognitive dysfunction. Polypharmacy is commonly used but supportive evidence is limited. Most fibromyalgia trials focus primarily on pain reduction with monotherapy. This trial compares a pregabalin-duloxetine combination to each monotherapy.

SUMMARY:

This double-blind randomized controlled trial demonstrates improved outcomes with a pregabalin-duloxetine combination over either single drug for fibromyalgia.

http://www.ncbi.nlm.nih.gov/pubmed/26982602

 

[Sushi]

This trial compares a pregabalin-duloxetine combination to each monotherapy.

That's Lyrica and Cymbalta for those who don't know the generic names.

 

[barbc56]

Thanks @Sushi I was getting ready to look these up. Unfortunately, I can't take either one but would be interested if others have tried this.

Interesting topic @shannah

 

[panckage]

Lyrica makes me brain dead and cymbalta makes me sleep for 20 hours a day. I guess being braindead and unconciious is one way to deal with pain