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CMX001

Messages
64
Say what!!?!!!! 2017!!! (sad face)

Yes, and that's probably on fast-track as well, but I could be wrong.

I'm interested in antivirals myself but haven't had any tests done specifically for viruses, only bacterial infections which I'm treating with antibiotics.

Are there any specific clinical differences between viral CFS/ME and "non-viral", if there is indeed such a thing? In other words, any differences between those who had significant relief from symptoms by using antivirals as opposed to those who haven't used it because they test negative for known viruses?
 

Sasha

Fine, thank you
Messages
17,863
Location
UK
Yes, and that's probably on fast-track as well, but I could be wrong.

I'm interested in antivirals myself but haven't had any tests done specifically for viruses, only bacterial infections which I'm treating with antibiotics.

Are there any specific clinical differences between viral CFS/ME and "non-viral", if there is indeed such a thing? In other words, any differences between those who had significant relief from symptoms by using antivirals as opposed to those who haven't used it because they test negative for known viruses?

Sad face over here as well - hang on, this one's my favourite :ill: - but the FDA seems to be interested in getting new mechanisms in place for a fast-track - or unmet-needs track - or something-else track - that can actually cut through some of this slowness. I'm no expert on their procedures but maybe we can expect something sooner than 2017 with this drug.
 

Gypsy

Senior Member
Messages
123
Location
USA
Yes, and that's probably on fast-track as well, but I could be wrong.

I'm interested in antivirals myself but haven't had any tests done specifically for viruses, only bacterial infections which I'm treating with antibiotics.

Are there any specific clinical differences between viral CFS/ME and "non-viral", if there is indeed such a thing? In other words, any differences between those who had significant relief from symptoms by using antivirals as opposed to those who haven't used it because they test negative for known viruses?

You would definitely want to get tested for the specific viruses the drug would treat first. If there is no virus present, the drug will have no job to do. :)

It looks like CMX001 is being developed for CMV. Valcyte is only "approved" for CMV but is also prescribed for HHV6 and sometimes EBV. Hopefully this new drug will target all 3 with a minimal of side effects.....in 2017 (boo!)

Testing is highly subjective, what one doctor views as an active infection another may not.
 

Gypsy

Senior Member
Messages
123
Location
USA
?
Gypsy

There is a long list of viruses that CMX will target though the trials are for CMV.

Sushi

Really? But I would assume they are all in the herpes virus family? I would be incredible to have one drug target so many viruses.
 

Sushi

Moderation Resource Albuquerque
Messages
19,935
Location
Albuquerque
?

Really? But I would assume they are all in the herpes virus family? I would be incredible to have one drug target so many viruses.

You can find the list on the CMXoo1 research pages--there are lots of different sites, but that is where I saw the list.

Here is what I just found with a quick google:
CMX001’s potential to be a safe and efficacious broad-spectrum
antiviral for the treatment of double-stranded DNA viral infections,


Sushi
 
Messages
59
Location
Southern USA
This very well could be the magic drug that [most of us] have been waiting for. A spokesman for the Drug manufacturer said their goal is to make it commercially available by 2016. Only 2 more years!
 
Messages
97
Why wait? If enough people are interested, it can be quite affordable to get private labs to synthesize new drugs. As long as it is for "research purposes" it is legal in the US, as patents cannot be issued until all trials are complete.