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Chinese anti-inflammatory herb effective for RA

Discussion in 'Other Health News and Research' started by natasa778, Apr 16, 2014.

  1. natasa778

    natasa778 Senior Member

  2. Hutan

    Hutan Senior Member

    New Zealand
    Recent news on the Thunder God Vine.
    Celastrol, a molecule from the root has been found to possibly enhance action of leptin/ alleviate leptin resistance and so control obesity - in mice.

    Article on this (link below) notes leptin resistance is associated with a stress response in endoplasmic reticulum.

    And from this site:

    'Currently, thunder god vine is used as a traditional or folk remedy for excessive menstrual periods and autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, and lupus.'​
      • Laboratory findings suggest that thunder god vine may fight inflammation, suppress the immune system, and have anti-cancer effects.
      • Although early evidence is promising, there have been few high-quality studies of thunder god vine in people. Results from a large study funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), which compared an extract of thunder god vine root with a conventional medicine (sulfasalazine) for rheumatoid arthritis, found that participants’ symptoms (e.g., joint pain and swelling, inflammation) improved more significantly with thunder god vine than with sulfasalazine.
    Interesting given the work on leptin regarding ME/CFS. Caution warranted as the Thunder God Root has more in it than just the celastrol and there are side effects.
    Last edited: May 21, 2015

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