Choline on the Brain? A Guide to Choline in Chronic Fatigue Syndrome
Discuss the article on the Forums.

Chemotherapy and the Microbiome

Discussion in 'The Gut: De Meirleir & Maes; H2S; Leaky Gut' started by Wayne, Sep 29, 2015.

  1. Wayne

    Wayne Senior Member

    Ashland, Oregon
    It sounds like chemotherapy can be as bad as antibiotics for gut flora. Short article by Dr. David Perlmutter...

    Chemotherapy and the Microbiome

    Typically, when the chemotherapy agent is administered, there is irritation of the gut (mucositis), and, likely, this is what provoked the researchers to study the microbiome of these individuals.

    The study looked at the genetic signatures of the gut bacteria of 28 patients both before and after chemotherapy. None of the subjects received antibiotics. The authors found that chemotherapy had a dramatic effect on the gut organisms, stating in their conclusion:

    In summary, we found a profound disruption of the intestinal microbiome in terms of both taxonomic composition and metabolic capacity that may partly explain the acute inflammation, known as GI mucositis, observed after chemotherapy. This dysbiosis is also characteristic of other acute and chronic inflammatory conditions in mice as well as in humans, suggesting a causal role for the microbiome in chemotherapy-induced GI mucositis.​
    sarah darwins likes this.

See more popular forum discussions.

Share This Page