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AMPK Activation, mitochondria and Berberine

Discussion in 'General Treatment' started by Jenny TipsforME, Oct 29, 2015.

  1. Jenny TipsforME

    Jenny TipsforME Senior Member

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    I've recently been researching things that may help with walking for my blog and wanted to pick your informed brains about Berberine because this seems interesting for a number of reasons.

    This is the context from my blog

    https://tipsforme.wordpress.com/2015/10/19/resource-walking-problems/#ampk

    Berberine is a substance in plants but it can be bought as a fairly affordable supplement.

    It seems to have a range of benefits and I've seen on other threads pwme take it for other reasons. If you take it have you noticed any benefit in terms of muscle energy? Why do you take it? If you know of it, but don't use it why?

    Sciencey folk - is this the medication alluded to in the AMPK exercise paper? It says a drug already exists but I'm just trying to connect the dots.

    BTW these are other potential benefits

     
  2. ahmo

    ahmo Senior Member

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    Berberine is hard on the liver, not good for extended use, as far as I know. I used it w/ other natural anti-bacterials, using each 4 days at a time, over a couple months.
     
  3. adreno

    adreno PR activist

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    Lipoic acid increase AMPK.
     
  4. sillysocks84

    sillysocks84 Senior Member

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    clostridium butyricum is a probiotic that apparently can. If you have mercury issues ala can worsen symptoms unless you include it as a part of a protocol.
     
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  5. sillysocks84

    sillysocks84 Senior Member

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    Is lipoic acid different from alpha lipoic acid?
     
  6. adreno

    adreno PR activist

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    No.
     
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  7. Jenny TipsforME

    Jenny TipsforME Senior Member

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    @ahmo did you notice any impact on muscles or blood sugar?
     
  8. ahmo

    ahmo Senior Member

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    @Jenny TipsforME No, I didn't notice any. Mind you, I was engaged in intensive detox/elimination, and that's about all I could focus on.
     
  9. Jenny TipsforME

    Jenny TipsforME Senior Member

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    @ahmo it is very hard to keep track of everything, especially with fluctuations being the norm as well.

    @adreno I'll look up lipoic acid (I think this is on Myhill's list of mitochondria supplements).

    @sillysocks84 clostridium butyricum I've not heard of but interesting it's a probiotic too

    Berberine caught my attention because it seemed to do a few things at once. This obviously makes it more cost effective but also with so many symptoms I think that anything getting to root problems would knock out at least a handful of symptoms rather than one at a time.
     
  10. Jenny TipsforME

    Jenny TipsforME Senior Member

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    Yes CB seems to be in this category of doing several things at once. From another thread @adreno said:

    "Some effects of CB off the top of my head:

    - increases Tregs
    - shifts TH2 -> TH1
    - TLR4 antagonist
    - increases IL-10
    - increases AMPK
    - butyrate producer
    - reduces lactate
    - normalizes microflora
    - displaces pathogens (h. pylori, candida, e. coli, c. difficile, etc"
     
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  11. adreno

    adreno PR activist

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