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Allergies, IGE, mast cells, and cell damage

Discussion in 'Other Health News and Research' started by WillowJ, Apr 9, 2015.

  1. WillowJ

    WillowJ คภภเє ɠรค๓թєl

    WA, USA
    long article but well worth the read:
    by Carl Zimmer

    roller, sillysocks84, Bob and 3 others like this.
  2. roller

    roller wiggle jiggle

    IgE only when the intruder goes on a rampage

    helminths share sequences of genetic strings with plants/fungi/...
    e.g. the fluke Schisto japa appears to the body as birch pollen, as they have overlapping genes.

    Dunne concludes: nature planned to equip us (and plants...) with a defense to helminths and therefore made us allergic to helminths.
    unfortunately, the genes are overlapping (e.g. schisto = birch), and therefore we fall sick to birch pollen.
    i think, they couldnt be more wrong on this reasoning. correct me, if they mean something different.

    sure thing - i want to be allergic to helminths. what to do?
    stupidly, i was tested unallergic to the known culprits.

    option based on Medzhitov idee:
    reduce IGF-1 to increase injury caused by helminths

    option based on Dunne idee:
    become allergic to birch pollen (means, the allergens of the helminths i have)
    how? perhaps by applying pollen extract to tissue, ingesting... any ideas?
    Last edited: Jan 19, 2016
  3. roller

    roller wiggle jiggle

    looking at circumstantial evidence, allergies seem of utmost importance.
    faik humans and helminths have 100% same genetics, btw.

    and this has to do with the allergic response as well?
    Last edited: Jan 19, 2016

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