I have stage 3 adrenal fatigue with confirmed low cortisol and DHEA (as well as mild secondary hypothyroidism). Ever since experiencing an acute adrenal crisis about 3 years ago, I have tirelessly supplemented and experimented with various types of minerals, nutrients and desiccated organs and glands, addressing both thyroid and adrenal issues. Each time I have supplemented with a recommended supplement, I immediately experience adverse effects, from aggravated adrenal symptoms to neurological symptoms. These are typically unpleasant and discouraging. I took a micro dose of T4 once and was plagued with uncomfortable head pressure for months. That's probably a good indication of how weak my adrenal glands are. However, I've never experimented with hydrocortisone or pure cortisol drugs because no doctor would acknowledge or diagnose me with adrenal fatigue or Addisons since my cortisol levels are not low enough and my symptoms not so severe. I was browsing through StopTheThyroidMadness website (I am not a representative and this is not their product) and adrenal cortex was suggested since the cortex does not contain the adrenaline and it isn't suppose to be stimulating. So I purchased it and I took a small 10g dose (1/5 of a capsule) and to no surprise, the typical symptoms surfaced. Head pressure, nausea, brain fog, fatigue. I took this at about 1 pm. Then an hour later I started feeling somewhat energetic, a little more than usual. I eventually started getting a little hyper and felt a little euphoric. This is how I imagine I should be feeling at my age as I'm only in my mid-20s, so I assumed that I wasn't stimulated and that my cortisol was really increasing. I was getting spontaneous erections (sorry, TMI), and was buzzing around the house. This lasted for an hour or two. I then felt the slump and a little more tired than usual. My spur of energy had never happened before when supplementing, it was probably the most hyper I've felt in a very, very long time. Adrenal glandulars, natural thyroid and licorice root would all induce debilitating fatigue, so I was a little excited. The early evening slump bothered me though, I felt worse than usual. I think that this may work, but spreading the dose throughout the day may be better (despite it being a very small dose). I also of course want to avoid it at night since I want to sleep. Any advice/opinions? I can't believe I'm saying this but I'm at least feeling a little hopeful, something I haven't felt in a very, very long time and these are results I've never experienced. Thanks.