The 12th Invest in ME Research Conference June, 2017, Part 2
MEMum presents the second article in a series of three about the recent 12th Invest In ME International Conference (IIMEC12) in London.
Discuss the article on the Forums.


Discussion in 'Rituximab: News and Research' started by Sing, Oct 24, 2011.

  1. Sing

    Sing Senior Member

    New England
    PLEAESE COMMENT AFTER YOU WATCH THIS VIDEO. The video is about an athlete with CFS who fully recovered. NOT typical!

    Chronic Fatigue Syndrome: Study Supports Autoimmune Disease Theory
    Oct. 24, 2011
    A new study supports the theory that chronic fatigue syndrome is
    anautoimmune disease, offering patients with the controversial
    condition new hope for a cure.

    Two injections of the cancer drug Rituximab, which suppresses the
    immune system, relieved chronic fatigue symptoms in 10 of 15 patients
    several months later, according to a small Norwegian clinical trial.
    The drug works by depleting the body's B-cells, lymphocytes that
    release antibodies important for fighting infections. It has also been
    shown to relieve symptoms of rheumatoid arthritis, another autoimmune

    The study suggests antibodies might be misguidedly attacking patients'
    own tissues in chronic fatigue syndrome, and that the delayed relief
    from Rituximab is linked to the "gradual elimination of
    autoantibodies," ystein Fluge of Haukeland University Hospital in
    Bergen, Norway, and colleagues wrote in the journal PLoS One.

    The trial stemmed from a fluky finding: A patient taking Rituximab
    fornon-Hodgkin's lymphoma experienced an unexpected decrease in
    chronic fatigue symptoms. The researchers have now launched a phase 2
    clinical trial that will incorporate "maintenance" Rituximab
    injections three to 15 months after the initial treatment.

    The autoimmune theory of chronic fatigue syndrome was bolstered by a
    2009 study that linked the condition to a virus called XMRV. But the
    study was knocked down last month when nine independent labs failed to
    replicate the findings, leaving chronic fatigue patients -- many of
    whom battle skepticism about their condition -- still searching for

    For Becky Blanton, a freelance journalist in Richmond, Va., the virus
    link made sense. She fought what she thought was the flu two months
    before her diagnosis. And in the 19 years since, her symptoms have
    relapsed and remitted like those of multiple sclerosis, an autoimmune
    disease thought by some to be triggered by an infection.
    "I'm still convinced it's a virus," Blanton told at the time.

    So are several researchers. Although the authors of the Norwegian
    study failed to find evidence of a XMRV infection in their study
    subjects, an unknown virus could be triggering an autoimmune reaction.
    Guillain-Barre syndrome, a paralytic autoimmune disease caused by
    antibodies attacking the nervous system, can be triggered by a virus.

    Dr. Michael Busch, professor of laboratory medicine at University of
    California, San Francisco, and lead author of the XMRV knockdown
    study, said he hopes the research effort spurred by the wayward
    finding will continue.
    "A lot of new groups are searching and a lot of patients have stepped
    forward to try to identify a new virus," Busch told at the
    Kim McCleary, president and CEO of the Chronic Fatigue and Immune
    Dysfunction Syndrome Association of America, echoed Busch's optimism.

    "We're determined to translate the heightened attention and deeper
    engagement XMRV has attracted into sustainable progress," McCleary
    said. "There are many other solid leads that merit the same rigorous
    follow-up as XMRV has received over the past two years."
  2. Enid

    Enid Senior Member

    That's great to see - thanks Sing - research picking up for you there. Still a viral cause I see - never doubted it myself.
  3. shannah

    shannah Senior Member

    That's an old video they've paired up with the new research Sing. I remember seeing it months and months ago.

    Once that initial video plays, there are 2 more that play after it. One is another old one with Dr. Donnica on XMRV and another is with Holtthorf which I don't know when that was done.

    They could have paired the article up with better choices such as the one by Dr. Bell circulating lately.
  4. GaryK


    Canada Niagara Falls
    The Video was terrible! I was insulted by it. A person get sick(TRIATHLETE) then recovers 1and half years after being sick . Well that was my story only I wasnt an

    The Story needs to play out years later when she *MAY* relapse and disease symptoms change to Neurological immune Dysfuntion. I would then like to see her video... But TV loves to portray the short story with the ****CURE****;)

    Thumbs down for the Video BUT good they talked about the new studies with me/cfs and Rituximab:)
  5. urbantravels

    urbantravels disjecta membra

    Los Angeles, CA

    I left a comment letting them know what I thought of their choice of video.

    I'd like to encourage anyone who feels able (you do have to register to leave a comment) to leave whatever positive, intelligent comment you'd like to make. The few comments that are up there now seem to be mostly from cranks parroting the new "Auto-Immune Disease means nothing" meme that seems to have sprung up lately.

    While ABC deserves to get slapped for reycling that stupid video, I'd also like to support and encourage them for covering the Norwegian story at all - since the print story that appears on that page is a reasonable and good one and deserves to be acknowledged as such.
  6. maddietod

    maddietod Senior Member

    East Coast, USA
    Urban, your comment on the website is great. I wanted to get on and complain about the video, but couldn't think of enough positive things to say (although I liked and appreciated the article) to balance my frustration about the visual. Brain fog!
  7. Sing

    Sing Senior Member

    New England
    I really liked your comment and thought it spoke volumes. Everyone who reads it ought to understand the problem with the video. I also thought it was a very
    good response to the article, which is the real news. But we do need to help them get it into the right context.

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