I'm one who is struggling pretty bad with this symptom too. I was doing well and had zero excitotoxicity symptoms when I was doing methylation and had my glutathione up. I was able to go on hour long hikes and they made me feel better, not worse. However, methylation caused me severe cognitive dysfuntion, so while I suffered no physical aspects of the illness anymore, I could not hold conversations with people. My brain speed was ridiculously slow.
I went off all methylation supps, and it took 9 months or so, but I crashed physically. Then, I went to Las Vegas, and something in the environment did not agree with me. I started having severe tinnitus, and anxiety, basically severe excitotoxicity started. There are only 2 options for why this happend 1)mold, bacterial, or other neurotoxin got into my brain or 2) Heavy metals like aluminum got into my brain. In las vegas there is a TON of airplane trails that are known to release aluminum into the environment.
This leads me to hypothesize that excitotoxicity is caused by neurotoxins OR heavy metals. We eventually have to get whatever is infecting our brains out of there. I am currently looking for a doctor that can help me figure this out. I am going to do a hair analysis test too.
Glutathione levels going up helps a ton, however, catch 22 happens because once excitotoxicity gets bad enough the brain will not accept b12, and b12 will only worsen excitotoxicity. I once was able to handle b12, but now it makes my brain hurt.
To answer your question about adrenals, yes they will help, cortisol is anti inflammatory and counteracts neurotoxins in the brain. I think this is why some of us experience restlessness and an atractiveness to stress, our bodies are craving stress in order to stimulate more cortisol.