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Plasmacytoid Dendritic Cells in the Duodenum of Individuals Diagnosed with Myalgic Encephalomyelitis Are Uniquely Immunoreactive to Antibodies
to Human Endogenous Retroviral Proteins
in vivo 27: 177-188 (2013)
KENNY L. DE MEIRLEIR, SVETLANA F. KHAIBOULLINA, MARC FRÉMONT, JAN HULSTAERT, ALBERT A. RIZVANOV, ANDRÁS PALOTÁS and VINCENT C. LOMBARDI
http://www.wpinstitute.org/news/docs/invivo27_177-188_2013.pdf
to Human Endogenous Retroviral Proteins
in vivo 27: 177-188 (2013)
KENNY L. DE MEIRLEIR, SVETLANA F. KHAIBOULLINA, MARC FRÉMONT, JAN HULSTAERT, ALBERT A. RIZVANOV, ANDRÁS PALOTÁS and VINCENT C. LOMBARDI
http://www.wpinstitute.org/news/docs/invivo27_177-188_2013.pdf
An increasing body of evidence suggests that disruptions in the gut may contribute to the induction of neuroinflammation. Therefore, reports of human endogenous retroviral (HERV) expression in association with neuroinflammatory diseases prompted us to investigate the gut of individuals with ME for the presence of HERV proteins. In eight out of 12 individuals with ME, immunoreactivity to HERV proteins was observed in duodenal biopsies. In contrast, no immunoreactivity was detected in any of the eight
controls.