Hi
@Sundancer - sounds like we are going much the same route
I started taking 3000 mg glycine before bed a few years ago, plus I take more in the middle of the night. I also take l-theanine (for the brain to produce GABA) and plain GABA. And 5-htp before bed.
is there any way to cut up quotes in this forum? for easier reading? I'll post in blue for now.
yes, thats sort of my thing too, I also use lactobacillus Rhamnosus evere half a year, produces GABA in the gut. But it seems that until now it does not want to really settle there.
Now, I have just learned that low magnesium is related to middle of the night insomnia. I thought I was taking adequate magnesium but hair analysis has just showed that my calcium/magnesium ratio is very heavily skewed in favor of calcium and it was recommended that I stop calcium supplements, temporarily at least, which I have done. And I have jacked up my magnesium at night - 400 mg magnesium glycinate before bed and 200 to 400 more in the middle of the night. And I have finally started going back to sleep in the middle of the night, instead of being awake for hours (!) It feels too good to be true! Crossing my fingers ...
this is interesting, I use 300 mg glycinate before bed, that does help ( tried several forms of magnesium, this is decidedly the best, never thought of taking another one in the middle of the night though, worth a try)
My calcium is probably (too) low though, I will start taking sups. Asked GP to test levels beforehand but he didn't, think he forgot...
I also learned something interesting about msg - taurine is supposed to help with msg neurotoxicity - and B6 is necessary for the body to make taurine I already knew I needed a fair amount of B6 from Nutreval testing of 2010, and have been taking 100 mg P-5-P a day in divided doses, 50 mg each with breakfast and lunch. So I've just upped my P-5-P to 150 mg., still with breakfast and lunch because ironically enough it gives me insomnia at night.
curiouser and curiouser said alice...
I've used extra B6 to get more sleep, and it did work. I think ( now) that may have had a relation with the I think it's the called the transsulfuration , the conversion from homocysteine to sulfate.
But GP tested blood again and B6 is way too high now ( while i take only 10 mg) so for now I stopped taking it. He thinks that the tingling of hands ( and by now feet) is related to that. So I'm studing now what vcan be the reason that my body does not use up the stuff)
And B6 is necessary for proper magnesium absorption and utilization. It all ties together - so now I'm thinking that my extreme msg sensitivity may be due to low B6, when I feel up to staying awake 3/4 of the night, I'm going to try an experiment and see if I react as strongly to msg now that I have increased my B6 and magnesium.
Yes, it all ties together, and everybody's puzzle is a little different. I don't remember now how my therapists theorized this over exited glutamate route, there'll come a day that I start to post these things.
I generally wasn't waking up at 3:00 a.m., I was already awake from 12 or 1. And my heart didn't race and I generally didn't have night sweats - and because I'm sleeping better with more magnesium and less calcium, I think I found the culprit!
ah, sounds totally different, good that you've found your solution, not sleeping is the worst of all in my opinion.
For what it's worth, glycine initially caused a huge detox reaction for me, but starting very low and slow I was able to gradually build up my dose. I liked it so much for sleep, I wanted to keep taking it.
yes, it works wonders for sleep, but did not have much of a detoxreaction from it. Went from zero to 5 grams in 10 days without any problems..
Also, inositol and glutamine also helped with detoxing.
I'll keep that in mind and study upon it
I used to have detox symptoms much of the time, I reacted to so many things, and I don't any more. I think my detox pathways are finally working properly. Here's a very interesting article about Phase II liver detoxification, which mentions these 3 nutrients, among other things:
https://www.diagnose-me.com/treatment/liver-detoxification-phase-II-support.php[
that
looks interesting too, more homework for me, thanks!
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