My protocol is too long to type in. It's kindof too long to even be kept accurate. I change it all the time. Like I am about to add berberine to lower cholesterol and I have tentatively added forskohlii to "help my cells be more sensitive to thyroid hormone" but I am re-evaluating that decision. I leave things off because I run out of time to dish out all the vitamins and all sorts of crazy things (things I never used to do before there came to be so many vitamins). I take them all at once and then I get dehydrated from it so I split them up and then I never get around to taking the last batch. But I never actually forget my pills (I mean that I take the bulk of them almost every day my WHOLE LIFE (my mother stuffed them in me as a sickly sickly baby).
Supplement, Brand - Dose - Reason
Thorne Basic Nutrients IV with copper and iron and iodine - 3 of 6/day (1/2 a multi) - Trace minerals etc.
Vitamin A 10,000 IU (NOT beta carotene) (any brand) - 1/day - keratosis pilaris[10]; low ferritin, normal hemoglobin[11]
Thorne Basic B, active B complex - ~25mg (2/day) - Methylation[1]; energy (Kreb)
50mg P5P (Country Life) - 1/day - Methylation[1]; hypochlorhydria
800mcg methylfolate (Solgar) - 1/day - Methylation[1]
1g TMG (Soloray) - 1-2/day - Post-prandial methylation[1]
Mineral Ascorbate ( Ester C ) - 2g/day - Anti-oxidant; methylation[7]
10,000 IU Vitamin D (Superior Source sublingual) - (1/day, for 5 days/week) - VDR genetic defect; repeat blood test verified
1g d-alpha-tocopherol (any brand) - 1/day - Antioxidant; Offsets peroxisomal beta oxidation caused by DHEA; [2]
300mg gamma-tocopherol (LEF) - 1/day normally; 2/day allergy season - Proven to lower post-prandial blood sugar, which affects blood pressure
K2, one of: MK-7 100 mcg [3] (NOW); MK-4 15mg dose (OAR, Canadian brand) - 1/day (smaller dose); 1/week (larger dose) - Required to deposit calcium in bones instead of arteries; cleans calcium and plaque out of arteries; osteopenia
Calcium citrate + magnesium citrate 1:1 ratio (Nutricology) - 400-600mg, divided dose - Hypertension; VDR genetic defect; osteopenia; energy; normal sleep (low magnesium causes insomnia); citrate inhibits kidney stones
50mg Zinc piconolate (NOW) - 1/day normally; 2/day allergy season - Rebuild tissues destroyed by allergies; thyroid support during allergy season[4]; osteopenia; hypochlorhydria (achlorhydria during allergy season)[8]; methylation[5]
2 mg Copper piconolate (Thorne) - 2/day - Deficient per testing; Cross linking of collagen to prevent aneurism; assists wound healing[13]; osteopenia; arthritis; hypochlorhydria; methylation[6]
Cruciferous Veggie Extract (LEF) - Contains I3C, DIM, apigenin [8], broccoli, cabbage, cat’s claw, rosemary, watercress. - 1/day - Ward off cancer (make less cancer-causing hormones out of HRT)
1g Tyrosine (NOW) - 2-4/day, depending on protein consumption - To make enough thyroxine, dopamine, and adrenal hormone on a low protein diet. (low BH4 due to genetics, inability to excrete large amounts of ammonia)
Thyrocsin Thyroid Cofactors (Thorne) - 1/day - Thyroid support [12]
100mcg selenium, 225mcg iodine, 500mg tyrosine, 100mcg methylcobalamin (B12), 500mcg Cu picolinate, 200mg C, 100 IU E (d-alpha), ashwaghanda 150mg
Coleus Forskohlii 100mg (Thorne) - 1/day allergy season - Thyroid support [12]
Selenium 200mcg (any brand) - 1/day - Thyroid support [12]; low selenium in local soil; ward off breast cancer
Olive Leaf Extract (Soloray) - 1g/day - Lower blood pressure (strong ACE inhibitor); hypochlorhydria (kills pathogens in place of HCL)
DHEA oral pills that go through the liver - 75mg - Lowers & stabilizes blood pressure; Prevents constant panic attack/low blood sugar; Protects against glutamate toxicity (otherwise I am extremely sensitive to glutamate); Causes peroxisomal beta oxidation prevented by high dose Vitamin E (higher than I take)
Pregnenolone - 30-50mg (currently 50) - Balance DHEA (makes progesterone); anti-cancer; for the brain
Melatonin - 6mg - Second strongest antioxidant for the brain next to dopamine.
Estradiol - ?? dose given by injection
Progesterone - ?? prescription
CoQ10 (ubiquinol, active form) - 200mg/day - Heart health; Kreb cycle/energy
1g. Omega-3 - 2/day - Heart health
Spirulina 500mg (Healthy Origins) - 21/day allergy season - (10.5g)
Significantly reduce allergy symptoms
D-mannose &/or cranberry - As needed for UTI - Treat UTI (to protect blood pressure)
Sufficient sleep - Blood pressure rises w/o sufficient sleep
New Additions:
Nattokinase - 2000 FU (1/day) - Clean arteries (plaque detected in carotid artery via ultrasound)
Pomegranate (POM) - 4 oz./day (5 days/week only – inhibits CYP3A4) - Melts plaque 13% in 3 months
Pantethene - 900mg total (2/day) - Adrenal support, Lower cholesterol
500 mcg Chromium picolinate (Thorne) - 1/day - Lower post prandial blood sugar and thus blood pressure
Vanadyl sulfate (LEF) - 1/day - Lower post prandial blood sugar and thus blood pressure
40mg UC-II (LEF) - 1/day - Desensitize immune system to collagen fragment to prevent mounting an allergy attack
PQQ 10mg, R-lipoic acid 100mg (LEF) - 1/day - Add mitochondria (for sports)
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1. Active B supplements required to manage homocysteine due to genetic defects in methyl cycle.
(This ENTIRE protocol required to normalize homocysteine: 2Thorne Basic B – divided dose, 2g TMG, 50mg P5P, 800mcg mfolate, D in blood at 70, sufficient anti-oxidants and Zn, Cu, Mg)
2. High dosage required since I have severe allergies which mobilize the immune system and cause high oxidative stress
3. MK-7 is toxic in a much higher dose; MK-4 is not.
4. Theoretically I supplement zinc until I can breathe during allergy season. Actually I stop at 100mg. During a cold it takes 150 mg for me to breathe but a cold does not last as long…I appear to be unwilling to take over 100mg zinc for more than a few days.
5. Cofactor of methionine synthase
6. Lack of copper causes same symptoms as B12 deficiency (affects methylation)
7. Free radicals dysregulate the methyl cycle
8. Apigenin is an aromatase inhibitor; also strongly anti-cancer
9. Zinc + P5P required to make HCL
10. keratosis pilaris is caused by Vitamin A deficiency or inability to convert beta carotene to Vitamin A.
11. Retinol Binding Protein required to ferry iron around
12. During allergy season TSH moves from 2.1->3.2 and higher, raising cholesterol and blood pressure and slowing GFR, and as it keeps moving up the adrenal gland goes out causing low blood pressure, a need for salt to prevent fainting, and no energy whatsoever to lift a finger (thyroid winds down). The climb of TSH is slowed by large zinc intake but not stopped. More thyroid and adrenal support needed during allergy season. After allergy season GFR, thyroid, and adrenal return to normal as measured by creatinine, BUN, Cytatin-C, TSH.
13. When I take copper my wounds heal. Otherwise not, even w/o excessive zinc.