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Created in 2008, Phoenix Rising is the largest and oldest forum dedicated to furthering the understanding of, and finding treatments for, complex chronic illnesses such as chronic fatigue syndrome (ME/CFS), fibromyalgia, long COVID, postural orthostatic tachycardia syndrome (POTS), mast cell activation syndrome (MCAS), and allied diseases.
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Coincidence I hope, but my liver has gone crazy in the last 6 months. My enzymes have always been well within normal values, but with no change in diet I all of a sudden have a fatty liver with inflammation only in the lobe that is closer to middle of the body.
They just did another Hepatitis panel on me, but it's my third one. Seems like it has been every 5 years they do one and it is always negative. I have no tattoo's, so I expect my last one is negative to. I hope
No tattoos is good advice for anyone, but especially anybody with ME. Tattoos are basically permanent vaccines. It permanently aggravates the immune system, the immune cells absorb the ink and hold it in place.
Do you have any links for this? As so many people are tattooed, it should be easy to research it.
I have a tattoo...maybe I'll start a poll here.
Done it - here it is.
Although ferritin is widely recognized as being secreted by hepatocytes and
macrophages, its production by the mast cell [195] is far less appreciated. Hyperferritinemia
is quite common in mast cell disease [62],yet often it is misinterpreted as hemochromatosis
@alex3619 have you read this:
Although ferritin is widely recognized as being secreted by hepatocytes and
macrophages, its production by the mast cell [195] is far less appreciated. Hyperferritinemia
is quite common in mast cell disease [62], yet often it is misinterpreted as hemochromatosis
(even in the absence of an identifiable HFE mutation) or, in the patient who has received red
cell transfusions for any reasons, hemosiderosis. [196] It can be tempting to attribute the
entirety of the observed hyperferritinemia in an MCAS patient to transfusional hemosiderosis
if the patient has any transfusion history, but two clues will suggest that a not insignificant
portion of the elevation in ferritin is of inflammatory origin. First, the serum ferritin level
often is considerably higher than would be expected purely from the degree of hemosiderosis
attendant to the extent of the transfusion history. Second, while the hyperferritinemia of
transfusional hemosiderosis marches in relative lockstep with the transfusion history, the
hyperferritinemia of inflammation (MCAS-driven or otherwise) is highly variable from one
determination to the next.
Mast cell disease has been clearly associated with obesity and with diabetes mellitus
(both types) [197, 198]; of note, both obesity and diabetes mellitus (both types) are now
clearly recognized as chronic systemic inflammatory conditions. Mast cells have been
identified as effector cells in metabolic syndrome, too. [199] Given the intimate involvement
of PGD2 and its metabolites in at least one key adipose management pathway [200], it is not
surprising that there is a surfeit of lipid abnormalities in MCAS, too. [63] Elevations in total
cholesterol and low-density lipoproteins, and decreases in high-density lipoproteins and verylow-
density lipoproteins, are not uncommon. [197] Hypertriglyceridemia, too, is common and
often is the starkest lipid abnormality.
sigh, this is always a risk, isn't it?but I wonder if I am going to get hit with a side-diagnosis of hypochrondria, doh.
See what happens to people who complain.Bad news is they probably will want to do a liver biopsy. Oh well.
Alex is holding back, he is cured and wont tell us the treatment. I saw him running up this extremely steep hill near his place(queens road), he was running like a gazelle, an athlete. I saw him do this 2 days in a row, so he would smash the 2 day treadmill test??
LOL, heaps. Are you sure this was the road by his place, not the one in Skyrim*?
*a video game: screenshot