A.B.
Senior Member
- Messages
- 3,780
Personally I don't rule out the theory of central sensitisation - if that is defined as some kind of brain or nervous syndrome inflammation causing pain upon exertion such that the patient feels like serious damage is being inflicted even if the muscles themselves aren't being damaged by moving. Thing is, even if central sensitisation does explain the mechanism of ME/CFS in some patients, all the scientific evidence would show that GET still wouldn't be the cure.
The treatment for central sensitization is of course CBT (and probably GET). They have a product (CBT/GET), and by claiming that a thing such as central sensitization exists, they can create a market for this product. They also need to publish positive studies demonstrating efficacy but that's merely a formality with the kind of scientific standards they've adopted.
There are also a number of peripheral abnormalities that have been reported in patients (such as experiment with cell cultures showing abnormal metabolism) that seem to strongly contradict any models that attempt to reduce the illness to a central problem.