Violeta
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Chronic fatigue is the main fatigue-related issue in the clinic, and its prevalence is approximately 10% in the general population [3]. In particular, medically unexplained chronic fatigue, such as chronic fatigue syndrome (CFS), has a more serious impact on health-related quality of life than brain stroke, angina pectoris, or schizophrenia.
Additionally, central fatigue is a neuromuscular dysfunction, a notable feature of chronic fatigue, that is caused by biochemical alterations in the brain. Unlike peripheral fatigue, which is caused by energy-associated disturbances, mainly in muscles, central fatigue results from dysfunction of synaptic transmission in the central nervous system (CNS) [6]. Clinically, prolonged sleep disturbance and chronic stress are presumed to be inducers of central fatigue and are also major symptoms of pathologic central fatigue and chronic fatigue [7]. Important hypotheses on the pathophysiologic mechanisms of pathologic fatigue like CFS involve disruption of neuroendocrinological homeostasis resulting, for example, from chronic sleep deprivation (SD).
The remedy in this article is panax ginseng.
Additionally, central fatigue is a neuromuscular dysfunction, a notable feature of chronic fatigue, that is caused by biochemical alterations in the brain. Unlike peripheral fatigue, which is caused by energy-associated disturbances, mainly in muscles, central fatigue results from dysfunction of synaptic transmission in the central nervous system (CNS) [6]. Clinically, prolonged sleep disturbance and chronic stress are presumed to be inducers of central fatigue and are also major symptoms of pathologic central fatigue and chronic fatigue [7]. Important hypotheses on the pathophysiologic mechanisms of pathologic fatigue like CFS involve disruption of neuroendocrinological homeostasis resulting, for example, from chronic sleep deprivation (SD).
The remedy in this article is panax ginseng.