Sam7777
Senior Member
- Messages
- 115
I'll try to highlight some points.
- Absolutely know I was hurt by severe redistribution. 100% mercury issues.
- Still need to get a gene testing.
- Could be some other metals thrown in hiding, never have taken DMSA.
- Debating on doing Cutler and Shade protocol combined, people aren't keen but my research suggests its worthwhile.
- Initially 4 years ago I had a very bad episode with ALA at a time when I didn't understand the amalgam controversy, and that basically I guess you could view as the beginning of me being 'CFS' like in condition. I did some successful rounds of fdc in fall of 2013 but I was doing them with RLA. I tried to do an overly aggressive round again a year and a half ago this time with ALA (I got the tooth extracted in May 2013) and that knocked me hard for about 5 months, started up some small rounds in summer 2014 and just couldn't wake up to the damn alarm, couldn't handle even those doses. I've done rounds recently, and it seemed finally manageable at 5 mg with IMD and multivitamin. I've done larger RLA doses on Shade's protocol with positive reactions recently too.
- Not impressed with ALA in the literature, but NaRLA is too $. Regular RLA is still highly rated at online vendors. ALA can work, I've been reading a lot of Cutler success blog stories, but its long and grueling.
- ALA is a good chelator, RLA is a stellar neutraceutical, especially in high doses. ALA is the devil in high doses. ALA makes me especially feel unwell/crazy compared to RLA.
- I may resort to doing FDC with RLA, but I'm planning on sticking to 25 mg per dose of ALA, and perhaps doing Shade's protocol on different days. I still simply don't see a justification in Cutler's issues with RLA.
- What Shade's protocol and methylation have in common- nutrigenomics. Cutler's is a bit lacking in the area. But I still have not seen a better protocol in terms of consistent success stories.
- Shade's IMD seems to negate a lot of the discomfort of cutler's rounds, or LA in general.
- Triphala (clearway cofactors) and coffee enemas seem to be a big deal for me in terms of energy. Shade's theories on nrf2 seem to hold up and match the literature.
- I'm feeling a lot more open to the notion of methylation after spending a lot of time looking at the background stories of people who had pretty bad snp combos and had done cutlers protocols.
- A key consistent thing that has turned me away from methylation is that I don't have the sensitivities to these supplements that so many do. And since becoming interested, I've vetted it out. I've never had a noticeable positive or negative reaction to b12 and folate supplements of any type, nor to TMG and ALCAR while trying the protocols for periods.
- But I do react to chelation disproportionately compared to many. I react to thiols in food and supplements pretty significantly. I was ready to jump on a assumption of CBS but I'm reserving hasty conclusions. I feel there's more to it.
- Two examples of my point are here: 1 is a guy who has some pretty similar conditions to my own and to many poor responders of chelation, and he does not have CBS but he has issues with SOD and his ammonia. 2 is a pretty elaborate case for why CBS really messes up chelation (which I see some current large threads now on this, though this is all the first I'm hearing of it)
- http://howirecovered.com/my-genetics/
- http://www.heartfixer.com/AMRI-Nutrigenomics.htm#CBS (Cystathionine Beta Synthase) Explanation and Generic Plan of Action
- Which led me to come up with some consideration worthy supplements (I'm not about to jump into them blindly, I have reservations once again) but it may only be ya know, manganese and molybdenum which I was terribly low in on my hair test.
- So I guess I should ask a hypothetical. Let's say you are positive or heterozygous for some snps on these CBS/SOD/SUOX/BHMT what would you do? The heart doctor there is saying to get CBS under control before adding methylfolate and methylb12. He's worried about glutathione not helping process stuff. Which brings us back to using Chris Shade's protocol.
- What I notice in terms of methylation support that actually seems to help me, are just huge doses of good like thorne methyl support multivitamin multimineral, its not the individual vitamins and minerals that do much for me. And this is especially noticeable with RLA.
- But I threw together a list here of stuff that came up in some of these links that I could conceivably use to deal with these tricky snps
- P-5-P folinic acid hydroxycobalamin boron molybdenum vitamin e, mag, c, zinc, riboflavin serine or choline basically phosphylserine PS/PC etc TMG creatine orinthine and malic acid.
- My main goal really is to desensitize the sulfur reactions, so that I can do cutler, and do shade. But I'm coming to the conclusion after years of this bickering among protocols, that the science and literature suggest that no one is totally correct. Your snps can make your individual case very unforgiving. With such symptoms and stories it seems that methylation is always an underlying factor. I personally don't want to take any chances, so using nutrigenomics and fdc chelation in conjunction seems prudent.